Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14072895 | 0.79 | CYP3A4 (0.38) | EPHX1 | |
| SCHEMBL21727250 | 0.79 | CYP3A4 (0.38) | EPHX1 | |
| SCHEMBL14072936 | 0.79 | CYP3A4 (0.38) | EPHX1 | |
| SCHEMBL14305089 | 0.76 | TLR2 (0.32) | MCL1 | |
| SCHEMBL27076710 | 0.75 | EPHX2 (0.34) | MCL1EPHX2 | |
| SCHEMBL21420047 | 0.75 | EPHX2 (0.34) | MCL1EPHX2 | |
| SCHEMBL6982537 | 0.75 | EPHX2 (0.34) | MCL1EPHX2 | |
| SCHEMBL15839886 | 0.75 | EPHX2 (0.34) | MCL1EPHX2 | |
| SCHEMBL22879150 | 0.75 | EPHX1 (0.30) | EPHX1 | |
| SCHEMBL20640556 | 0.74 | EPHX2 (0.34) | MCL1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017106556-A1 | TANK-BINDING KINASE INHIBITOR COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2017-06-22 | — | — | WO | disclosed |