Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17913796 | 0.87 | KDM2B (0.34) | — | |
| SCHEMBL17747647 | 0.82 | MCL1 (0.32) | MCL1 | |
| SCHEMBL408327 | 0.81 | NR1H2 (0.40) | — | |
| SCHEMBL19015226 | 0.76 | EPHX1 (0.33) | MCL1 | |
| SCHEMBL3713407 | 0.76 | — | — | |
| SCHEMBL14699492 | 0.74 | KDM2B (0.30) | MCL1 | |
| SCHEMBL17913787 | 0.74 | KDM2B (0.37) | — | |
| SCHEMBL20588478 | 0.73 | KDM5A (0.31) | — | |
| SCHEMBL20585738 | 0.73 | KDM5A (0.31) | — | |
| SCHEMBL20585740 | 0.73 | KDM5A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008011130-A2 | AMIDE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-01-24 | — | — | WO | disclosed |