Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19015893 | 0.85 | KDM4E (0.55) | KDM4EGFERADAMTS4CA2CA1 | |
| SCHEMBL7879499 | 0.84 | TDP1 (0.55) | KDM4EGFERADAMTS4ALDH1A1MMP2 | |
| SCHEMBL29858116 | 0.82 | KDM4E (0.52) | KDM4EGFERADAMTS4CA2CA7 | |
| SCHEMBL21458999 | 0.82 | KDM4E (0.52) | KDM4EGFERADAMTS4CA2CA7 | |
| SCHEMBL19407479 | 0.82 | KDM4E (0.52) | KDM4EGFERADAMTS4CA2CA7 | |
| SCHEMBL19015948 | 0.79 | NPY5R (0.49) | KDM4EGFERADAMTS4CYSLTR1PSMB5 | |
| SCHEMBL18473182 | 0.76 | ADAMTS4 (0.57) | KDM4EGFERADAMTS4MMP2 | |
| SCHEMBL7890390 | 0.76 | ADAMTS4 (0.57) | KDM4EGFERADAMTS4MMP2 | |
| SCHEMBL19385953 | 0.73 | ADAMTS4 (0.45) | KDM4EADAMTS4ALDH1A1CYSLTR1CYP1A2 | |
| SCHEMBL28330143 | 0.72 | KDM4E (0.54) | KDM4EGFERALDH1A1CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2288615-B1 | SELECTIVE CASPASE INHIBITORS AND USES THEREOF | GENESIS TECH LTD (BB) | 2017-06-21 | — | — | EP | disclosed |