Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 20/20 | 0.80 |
| ▸ | CASP7 | P55210 | 13/20 | 0.80 |
| ▸ | CASP1 | P29466 | 8/20 | 0.68 |
| ▸ | CASP9 | P55211 | 5/20 | 0.68 |
| ▸ | CASP4 | P49662 | 2/20 | 0.54 |
| ▸ | CASP2 | P42575 | 1/20 | 0.51 |
| ▸ | CASP5 | P51878 | 1/20 | 0.51 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.51 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18782015 | 0.91 | CASP3 (0.66) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL18782029 | 0.89 | CASP3 (1.00) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL7888498 | 0.89 | CASP3 (1.00) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL9961954 | 0.89 | CASP3 (1.00) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL16376133 | 0.89 | CASP3 (1.00) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL18471461 | 0.88 | CASP3 (0.86) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL19015961 | 0.88 | CASP3 (0.73) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL19015930 | 0.86 | CASP3 (0.78) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL19015927 | 0.84 | CASP3 (0.67) | CASP3CASP7CASP1CASP9 | |
| SCHEMBL18781766 | 0.82 | CASP3 (0.88) | CASP3CASP7CASP1CASP9CASP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2288615-B1 | SELECTIVE CASPASE INHIBITORS AND USES THEREOF | GENESIS TECH LTD (BB) | 2017-06-21 | — | — | EP | disclosed |