Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5260761 | 0.92 | GPR119 (0.51) | GPR119MAPTALDH1A1TP53HTT | |
| SCHEMBL390132 | 0.82 | GPR119 (0.68) | GPR119MAPTALDH1A1TP53HTT | |
| SCHEMBL5265032 | 0.80 | MAPT (0.46) | GPR119MAPTALDH1A1TP53HTT | |
| SCHEMBL389195 | 0.79 | GPR119 (0.63) | GPR119MAPTALDH1A1TP53HTT | |
| SCHEMBL390189 | 0.78 | MAPT (0.62) | GPR119MAPTALDH1A1TP53HTT | |
| SCHEMBL389430 | 0.77 | GPR119 (1.00) | GPR119MAPTALDH1A1KMT2A | |
| SCHEMBL387746 | 0.77 | GPR119 (0.77) | GPR119MAPTALDH1A1TP53HTT | |
| SCHEMBL386411 | 0.77 | GPR119 (0.77) | GPR119MAPTALDH1A1TP53HTT | |
| SCHEMBL1071586 | 0.76 | GPR119 (0.66) | GPR119MAPTALDH1A1TP53HTT | |
| SCHEMBL5261798 | 0.76 | MAPT (0.50) | GPR119MAPTALDH1A1TP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2322150-A2 | Method of identifying GLP-1 secretagogues | Arena Pharmaceuticals, Inc. (US) | 2011-05-18 | — | — | EP | disclosed |