Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.53 |
| ▸ | CASP2 | P42575 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 4/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24690940 | 0.90 | FAAH (0.53) | GLP1RCASP2FAAHNAAAEPHX2 | |
| SCHEMBL24227203 | 0.89 | GLP1R (0.60) | GLP1RCASP2FAAHNAAADNM1 | |
| SCHEMBL13815476 | 0.88 | GLP1R (0.59) | GLP1RCASP2FAAHNAAADNM1 | |
| SCHEMBL19249030 | 0.88 | FAAH (0.55) | GLP1RCASP2FAAHNAAA | |
| SCHEMBL13553378 | 0.88 | FAAH (0.55) | GLP1RCASP2FAAHNAAA | |
| SCHEMBL14748061 | 0.87 | GLP1R (0.61) | GLP1RCASP2FAAHNAAADNM1 | |
| SCHEMBL14748065 | 0.87 | GLP1R (0.61) | GLP1RCASP2FAAHNAAADNM1 | |
| SCHEMBL14728241 | 0.87 | GLP1R (0.61) | GLP1RCASP2FAAHNAAADNM1 | |
| SCHEMBL13815852 | 0.87 | GLP1R (0.55) | GLP1RCASP2FAAHNAAADNM1 | |
| SCHEMBL18560514 | 0.87 | GLP1R (0.47) | GLP1RFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3685847-B1 | MODULATORS OF COMPLEMENT ACTIVITY | RA PHARMACEUTICALS INC (US) | 2023-01-11 | — | — | EP | disclosed |
| EP-3389692-B1 | MODULATORS OF COMPLEMENT ACTIVITY | RA PHARMACEUTICALS INC (US) | 2020-03-04 | — | — | EP | disclosed |
| WO-2017105939-A1 | MODULATORS OF COMPLEMENT ACTIVITY | RA PHARMACEUTICALS, INC. (US) | 2017-06-22 | — | — | WO | disclosed |