Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | AGER | Q15109 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4620997 | 0.81 | KDM4E (0.47) | SMN1; SMN2LMNAKDM4ETDP1ALDH1A1 | |
| 2-Mercaptonicotinic Acid SCHEMBL29382089 | 0.81 | KDM4E (0.63) | SMN1; SMN2LMNAKDM4ETDP1ALDH1A1 | |
| 2-Mercaptonicotinic Acid SCHEMBL261186 | 0.81 | KDM4E (0.63) | SMN1; SMN2LMNAKDM4ETDP1ALDH1A1 | |
| 2-Mercaptonicotinic Acid SCHEMBL29105774 | 0.79 | KDM4E (0.61) | SMN1; SMN2LMNAKDM4ETDP1ALDH1A1 | |
| SCHEMBL21995771 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAKDM4ETDP1ALDH1A1 | |
| SCHEMBL1326787 | 0.79 | PARP1 (0.56) | SMN1; SMN2LMNAKDM4ETDP1ALDH1A1 | |
| 2-Mercaptonicotinic Acid SCHEMBL29181672 | 0.79 | KDM4E (0.61) | SMN1; SMN2LMNAKDM4ETDP1ALDH1A1 | |
| 2-Mercaptonicotinic Acid SCHEMBL30605292 | 0.79 | KDM4E (0.61) | SMN1; SMN2LMNAKDM4ETDP1ALDH1A1 | |
| SCHEMBL27951997 | 0.79 | KDM4E (0.45) | SMN1; SMN2LMNAKDM4ETDP1ALDH1A1 | |
| 2-Mercaptonicotinic Acid SCHEMBL29105768 | 0.78 | KDM4E (0.45) | SMN1; SMN2LMNAKDM4ETDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102349-A1 | PROCESS FOR DEPIGMENTING KERATIN MATERIALS USING THIOPYRIDINONE COMPOUNDS | L'OREAL (FR) | 2017-06-22 | — | — | WO | disclosed |