Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.51 |
| ▸ | MLLT3 | P42568 | 1/20 | 0.46 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | UBE2N | P61088 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CPB1 | P15086 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19017617 | 0.82 | USP30 (0.56) | USP30MLLT3MLLT1MEN1KMT2A | |
| SCHEMBL24812338 | 0.81 | KDM4E (0.45) | USP30MLLT3MLLT1MEN1KMT2A | |
| SCHEMBL69486 | 0.81 | KDM4E (0.55) | USP30KDM4EL3MBTL1CPB1CPB2 | |
| SCHEMBL6408184 | 0.81 | TLR2 (0.43) | KMT2AKDM4EMAPTALDH1A1TDP1 | |
| SCHEMBL19017584 | 0.81 | USP30 (0.55) | USP30 | |
| SCHEMBL71789 | 0.81 | MEN1 (0.59) | USP30MEN1KMT2AKDM4EMAPT | |
| SCHEMBL71030 | 0.80 | USP30 (0.54) | USP30MLLT3MLLT1ALDH1A1KDM4C | |
| SCHEMBL19017764 | 0.80 | GRM5 (0.52) | USP30MLLT3MLLT1 | |
| SCHEMBL27894425 | 0.80 | KDM4E (0.54) | USP30KDM4EL3MBTL1CPB1CPB2 | |
| SCHEMBL2498081 | 0.79 | MLLT3 (0.46) | MLLT3MLLT1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4122929-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2023-01-25 | — | — | EP | disclosed |
| WO-2017103614-A1 | Novel Compounds | MISSION THERAPEUTICS LIMITED (GB) | 2017-06-22 | — | — | WO | disclosed |