Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18883619 | 0.76 | — | — | |
| SCHEMBL59920 | 0.76 | — | — | |
| SCHEMBL19018351 | 0.76 | — | — | |
| SCHEMBL713529 | 0.76 | APLNR (0.37) | APLNR | |
| SCHEMBL21447097 | 0.74 | — | — | |
| SCHEMBL11462996 | 0.74 | KDM4E (0.38) | KDM4EMAPTAPOBEC3G | |
| SCHEMBL13149910 | 0.71 | — | — | |
| SCHEMBL75036 | 0.70 | APLNR (0.35) | APLNR | |
| SCHEMBL18979032 | 0.68 | APLNR (0.34) | APLNR | |
| SCHEMBL7387353 | 0.68 | MAPK1 (0.31) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571871-B1 | Process for the preparation of chiral triazolones | SANDOZ AG (CH) | 2017-06-21 | — | — | EP | disclosed |