Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19009072 | 0.80 | L3MBTL1 (0.50) | EPHX1HTTTSHRALDH1A1L3MBTL1 | |
| SCHEMBL20746923 | 0.76 | IDO1 (0.44) | EPHX1HTTTSHRALDH1A1L3MBTL1 | |
| SCHEMBL11314245 | 0.75 | EPHX1 (0.46) | EPHX1HTTTSHRALDH1A1L3MBTL1 | |
| SCHEMBL11523980 | 0.74 | EPHX1 (0.54) | EPHX1HTTTSHRALDH1A1L3MBTL1 | |
| SCHEMBL28517016 | 0.73 | EPHX1 (0.52) | EPHX1HTTTSHRALDH1A1L3MBTL1 | |
| SCHEMBL9182141 | 0.68 | EPHX1 (0.74) | EPHX1HTTTSHRALDH1A1L3MBTL1 | |
| SCHEMBL28501781 | 0.68 | EPHX1 (0.52) | EPHX1HTTTSHRALDH1A1L3MBTL1 | |
| SCHEMBL11314249 | 0.68 | EPHX1 (0.45) | EPHX1HTTTSHRALDH1A1L3MBTL1 | |
| SCHEMBL26816546 | 0.68 | EPHX1 (0.61) | EPHX1HTTTSHRALDH1A1L3MBTL1 | |
| SCHEMBL29657372 | 0.67 | NQO1 (0.59) | EPHX1TSHRALDH1A1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170174639-A1 | EIS INHIBITORS | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2017-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170174639-A1 | EIS INHIBITORS | ABCC1, ATP5ME, ABCG2 | EPHX1 1778/4885TAS1R3 4352/4885TAS1R1 4219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.