Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 17/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.36 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3781513 | 0.82 | CHEK1 (0.45) | SLC22A12ARPLA2G7CYP3A4CYP2C8 | |
| SCHEMBL2445697 | 0.81 | AR (0.44) | SLC22A12ARCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL12216030 | 0.80 | MAP4K4 (0.40) | SLC22A12ARPLA2G7CYP2C9CYP2C19 | |
| SCHEMBL2440738 | 0.80 | HTR2A (0.50) | SLC22A12AR | |
| SCHEMBL378727 | 0.78 | SYK (0.43) | SLC22A12PLA2G7 | |
| SCHEMBL2441913 | 0.78 | GRIN2B (0.41) | SLC22A12AR | |
| SCHEMBL379029 | 0.76 | MAP4K4 (0.46) | SLC22A12ARCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL12216031 | 0.76 | AR (0.41) | SLC22A12AR | |
| SCHEMBL378721 | 0.76 | HTR2A (0.46) | SLC22A12AR | |
| SCHEMBL2446966 | 0.76 | AR (0.41) | SLC22A12ARNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2961744-B1 | INTERMEDIATES FOR USE IN THE PREPARATION OF INDAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | ARRAY BIOPHARMA INC (US) | 2017-06-28 | — | — | EP | disclosed |