SCHEMBL1902016

SCHEMBL1902016

O=C(OC1CCCCC1)C1CC=CCC1C(=O)OC1CCCCC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP7 O15540 1/20 0.42
FABP5 Q01469 1/20 0.42
EPHX1 P07099 2/20 0.42
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
CYP2C19 P33261 2/20 0.40
MEN1 O00255 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
ALOX12 P18054 1/20 0.40
KMT2A Q03164 1/20 0.40
CHRM2 P08172 2/20 0.40
CHRM4 P08173 2/20 0.40
CHRM5 P08912 2/20 0.40
CHRM1 P11229 2/20 0.40
CHRM3 P20309 2/20 0.40
CYP19A1 P11511 4/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7721103 0.93 KDM4E (0.51) FABP7FABP5EPHX1KDM4EALDH1A1
SCHEMBL5518261 0.91 EPHX1 (0.42) FABP7FABP5EPHX1KDM4EALDH1A1
SCHEMBL5523570 0.87 POLB (0.46) FABP7FABP5EPHX1KDM4EALDH1A1
SCHEMBL5530961 0.87 EPHX1 (0.42) FABP7FABP5EPHX1ALDH1A1CYP2C19
SCHEMBL5524061 0.84 NAAA (0.41) FABP7FABP5EPHX1ALDH1A1CYP2C19
SCHEMBL5515720 0.83 CYP2C19 (0.40) FABP7FABP5EPHX1CYP2C19MEN1
SCHEMBL1297428 0.82 EPHX1 (0.48) FABP7FABP5EPHX1CYP2C19CHRM2
SCHEMBL2035380 0.82 EPHX1 (0.48) FABP7FABP5EPHX1CYP2C19CYP3A4
SCHEMBL1296625 0.82 EPHX1 (0.48) FABP7FABP5EPHX1CYP2C19CYP3A4
SCHEMBL5520504 0.82 GAA (0.41) FABP7FABP5EPHX1CYP2C19MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1063279-B1 Refrigerator oil for carbon dioxide refrigerant, and method of using it for lubrication IDEMITSU KOSAN CO (JP) 2014-07-02 EP disclosed
US-8324140-B2 Refrigerating machine oil composition for carbon dioxide refrigerant IDEMITSU KOSAN CO., LTD. (JP) 2012-12-04 US disclosed
EP-2325290-A1 Refrigerator oil composition, and method of using the composition for lubrication IDEMITSU KOSAN CO., LTD. (JP) 2011-05-25 EP disclosed
EP-1243641-B1 USE OF A LUBRICATING OIL COMPOSITION CONTAINING CYCLIC ORGANOPHOSPHORUS COMPOUND IDEMITSU KOSAN CO (JP) 2009-03-18 EP disclosed
US-7282601-B2 Dicarboxylic diester, process for producing the same, and refrigerating machine lubricating oil comprising the ester NEW JAPAN CHEMICAL CO., LTD. (JP) 2007-10-16 US disclosed
US-7271282-B1 Dicarboxylic diester, process for producing the same, and refrigerating machine lubricating oil comprising the ester NEW JAPAN CHEMICAL CO., LTD. (JP) 2007-09-18 US disclosed
US-20060128576-A1 Refrigerating machine oil composition for carbon dioxide refrigerant IDEMITSU KOSAN CO., LTD. (JP) 2006-06-15 US disclosed
US-7018961-B2 Refrigerating machine oil composition for carbon dioxide refrigerant IDEMITSU KOSAN CO., LTD. (JP) 2006-03-28 US disclosed
US-20050038283-A1 Dicarboxylic diester, process for producing the same, and refrigerating machine lubricating oil comprising the ester NEW JAPAN CHEMICAL, CO., LTD. (JP) 2005-02-17 US disclosed
US-6815402-B2 ONE COMPOUND SELECTED FROM SPECIFIC CYCLIC ORGANIC PHOSPHORUS THE LUBRICATING OIL COMPOSITION EXHIBITS EXCELLENT EXTREME PRESSURE PROPERTY, SEIZURE RESISTANCE AND WEAR RESISTANCE AND IS ADVANTAGEOUSLY USED AS BEARING OIL, GEAR OIL, HYDRAULIC OIL IDEMITSU KOSAN CO., LTD. (JP) 2004-11-09 US disclosed
EP-1227078-A1 DICARBOXYLIC DIESTER, PROCESS FOR PRODUCING THE SAME, AND REFRIGERATING MACHINE LUBRICATING OIL COMPRISING THE ESTER NEW JAPAN CHEMICAL CO.,LTD. (JP) 2002-07-31 EP disclosed
CN-1361762-A Dicarboxylic diester, process for producing the same, and refrigerating machine lubricating oil comprising the ester NEW JAPAN CHEM CO LTD (JP) 2002-07-31 CN disclosed
EP-1225213-A1 LUBRICATING OIL FOR REFRIGERATOR, HYDRAULIC FLUID COMPOSITION FOR REFRIGERATOR AND METHOD FOR LUBRICATION OF REFRIGERATOR NEW JAPAN CHEMICAL CO.,LTD. (JP) 2002-07-24 EP disclosed
EP-1203807-A1 REFRIGERATING MACHINE OIL COMPOSITION FOR CARBON DIOXIDE REFRIGERANT Idemitsu Kosan Co., Ltd. (JP) 2002-05-08 EP disclosed
US-6354094-B2 CO2 REFRIGERANT; ESTER-BASED LUBRICATING OIL SUCH AS A MIXED C 8-9 MIXED BRANCHED FATTY ACID ESTER OF PENTAERYTHRITOL OR A CARBONATE; CAN BE STABLY USED FOR A LONG PERIOD OF TIME IN A COMPRESSION REFRIGERATION CYCLE IDEMITSU KOSAN CO., LTD. (JP) 2002-03-12 US disclosed
US-6306803-B1 OXYGEN CONTAINING ORGANIC COMPONENT AND METAL SALT OF CARBOXYLIC ACID IDEMITSU KOSAN CO., LTD. (JP) 2001-10-23 US disclosed
US-20010027655-A1 Refrigerator oil composition, and method of using the composition for lubrication IDEMITSU KOSAN CO., LTD. (JP) 2001-10-11 US disclosed
US-6263683-B1 CARBON DIOXIDE AS ESSENTIAL COMPONENT AND A ESTER OF PENTAERYTHRITOL WITH C8-C9 FATTY ACID IDEMITSU KOSAN CO., LTD. (JP) 2001-07-24 US disclosed
EP-1063279-A1 Refrigerator oil for carbon dioxide refrigerant, and method of using it for lubrication Idemitsu Kosan Co., Ltd. (JP) 2000-12-27 EP disclosed
EP-1008643-A2 Refrigerator oil composition, and method of using the composition for lubrication IDEMITSU KOSAN COMPANY LIMITED (JP) 2000-06-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050038283-A1 Dicarboxylic diester, process for producing the same, and refrigerating machine lubricating oil comprising the ester SCO2, PDHX, DECR2 FABP7 4409/4885FABP5 3827/4885EPHX1 279/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.