Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15623808 | 0.83 | ALDH1A1 (0.53) | ALDH1A1PKMSMN1; SMN2SLC1A2MME | |
| SCHEMBL5705701 | 0.76 | SMN1; SMN2 (0.50) | ALDH1A1PKMSMN1; SMN2MMESLC6A2 | |
| SCHEMBL542270 | 0.76 | ALDH1A1 (0.50) | ALDH1A1PKMSMN1; SMN2MMELMNA | |
| SCHEMBL8763475 | 0.75 | ALDH1A1 (0.38) | ALDH1A1PKMSMN1; SMN2SLC1A2KMT2A | |
| SCHEMBL5703427 | 0.74 | SMN1; SMN2 (0.41) | ALDH1A1SMN1; SMN2KMT2AMEN1TAAR1 | |
| SCHEMBL2675329 | 0.74 | SMN1; SMN2 (0.41) | ALDH1A1SMN1; SMN2KMT2AMEN1TAAR1 | |
| SCHEMBL9658608 | 0.74 | MAPT (0.35) | ALDH1A1PKMSMN1; SMN2SLC1A2KMT2A | |
| SCHEMBL9658488 | 0.74 | MAPT (0.35) | ALDH1A1PKMSMN1; SMN2SLC1A2KMT2A | |
| SCHEMBL3736109 | 0.69 | ALDH1A1 (0.35) | ALDH1A1PKMSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL698898 | 0.67 | ALDH1A1 (0.56) | ALDH1A1PKMSMN1; SMN2SLC1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110117106-A1 | USES OF CALPAIN INHIBITORS TO INHIBIT INFLAMMATION | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2011-05-19 | — | — | US | disclosed |
| EP-0546017-A1 | SILAGE ADDITIVE | ZENECA LIMITED (GB) | 1993-06-16 | — | — | EP | disclosed |
| WO-1992003933-A1 | SILAGE ADDITIVE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-19 | — | — | WO | disclosed |