Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 20/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23731474 | 1.00 | HPGDS (0.67) | HPGDS | |
| SCHEMBL18987576 | 0.91 | HPGDS (0.72) | HPGDS | |
| SCHEMBL18987575 | 0.91 | HPGDS (0.72) | HPGDS | |
| SCHEMBL23731084 | 0.88 | HPGDS (0.68) | HPGDS | |
| SCHEMBL18987442 | 0.88 | HPGDS (0.67) | HPGDS | |
| SCHEMBL19021410 | 0.88 | HPGDS (0.67) | HPGDS | |
| SCHEMBL18987444 | 0.88 | HPGDS (0.67) | HPGDS | |
| SCHEMBL18988756 | 0.88 | HPGDS (0.67) | HPGDS | |
| SCHEMBL18988758 | 0.88 | HPGDS (0.67) | HPGDS | |
| SCHEMBL18987595 | 0.87 | HPGDS (0.66) | HPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017103851-A1 | QUINOLINE-3-CARBOXAMIDES AS H-PGDS INHIBITORS | ASTEX THERAPEUTICS LIMITED (GB) | 2017-06-22 | — | — | WO | disclosed |