Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 20/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL389892 | 0.91 | GPR119 (0.68) | GPR119CYP2C9 | |
| SCHEMBL27734747 | 0.91 | GPR119 (0.70) | GPR119CYP2C9 | |
| SCHEMBL389473 | 0.90 | GPR119 (0.70) | GPR119CYP2C9KCNH2 | |
| SCHEMBL389516 | 0.90 | GPR119 (0.69) | GPR119CYP2C9 | |
| SCHEMBL390447 | 0.89 | GPR119 (0.68) | GPR119CYP2C9KCNH2 | |
| SCHEMBL1082296 | 0.88 | GPR119 (0.67) | GPR119CYP2C9 | |
| SCHEMBL389232 | 0.88 | GPR119 (0.67) | GPR119CYP2C9 | |
| SCHEMBL391444 | 0.87 | GPR119 (0.66) | GPR119CYP2C9 | |
| SCHEMBL388981 | 0.87 | GPR119 (0.66) | GPR119CYP2C9KCNH2 | |
| SCHEMBL2403026 | 0.87 | GPR119 (0.71) | GPR119CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2322150-A2 | Method of identifying GLP-1 secretagogues | Arena Pharmaceuticals, Inc. (US) | 2011-05-18 | — | — | EP | disclosed |