Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ADH1C | P00326 | 1/20 | 0.41 |
| ▸ | ADH1A | P07327 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19002588 | 0.98 | L3MBTL1 (0.59) | L3MBTL1MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL19049407 | 0.87 | L3MBTL1 (0.56) | L3MBTL1MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL30090134 | 0.86 | L3MBTL1 (0.58) | L3MBTL1MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL10677454 | 0.85 | L3MBTL1 (0.59) | L3MBTL1MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL25982230 | 0.85 | L3MBTL1 (0.63) | L3MBTL1MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL6607603 | 0.84 | L3MBTL1 (0.57) | L3MBTL1MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL4163355 | 0.84 | L3MBTL1 (0.47) | L3MBTL1MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL30251238 | 0.82 | L3MBTL1 (0.55) | L3MBTL1MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL664692 | 0.82 | L3MBTL1 (0.55) | L3MBTL1MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL22448021 | 0.82 | L3MBTL1 (0.56) | L3MBTL1MEN1KMT2AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017106134-A1 | BENZIMIDAZOLES AND INDOLES AS TARO INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2017-06-22 | — | — | WO | disclosed |