Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.34 |
| ▸ | CPB1 | P15086 | 1/20 | 0.34 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10288521 | 0.87 | LMNA (0.47) | CYP2C9TSHRCYP2C19MTORHRH4 | |
| SCHEMBL12019273 | 0.84 | CYP2C9 (0.41) | CYP2C9TSHRCYP2C19MTORHRH4 | |
| SCHEMBL19009013 | 0.83 | CYP2C9 (0.46) | CYP2C9TSHRCYP2C19MTORHRH4 | |
| SCHEMBL10272325 | 0.83 | CYP2C9 (0.40) | CYP2C9TSHRCYP2C19MTORHRH4 | |
| SCHEMBL14230528 | 0.81 | CYP2C9 (0.39) | CYP2C9TSHRCYP2C19MTORHRH4 | |
| SCHEMBL12017874 | 0.80 | NTRK1 (0.38) | CYP2C9TSHRCYP2C19MTORHRH4 | |
| SCHEMBL19000039 | 0.79 | S1PR1 (0.45) | CYP2C9TSHRCYP2C19MTORHRH4 | |
| SCHEMBL14665172 | 0.77 | CYP2C9 (0.47) | CYP2C9TSHRCYP2C19MTORHRH4 | |
| SCHEMBL12174842 | 0.77 | CYP2C9 (0.50) | CYP2C9TSHRCYP2C19MTORHRH4 | |
| SCHEMBL27340963 | 0.77 | CYP2C9 (0.50) | CYP2C9TSHRCYP2C19MTORHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017106607-A1 | POLYCYCLIC TLR7/8 ANTAGONISTS AND USE THEREOF IN THE TREATMENT OF IMMUNE DISORDERS | MERCK PATENT GMBH (DE) | 2017-06-22 | — | — | WO | disclosed |