SCHEMBL19026412

SCHEMBL19026412

CC(C)[C@H](NC(=O)CCOCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O)C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(CO)cc1

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ FAP Q12884 5/20 0.39
▸ OPRK1 P41145 2/20 0.37
▸ FURIN P09958 2/20 0.35
▸ MAP1LC3B Q9GZQ8 2/20 0.35
▸ NPY1R P25929 2/20 0.34
▸ NPY4R P50391 2/20 0.34
▸ GLP1R P43220 3/20 0.33
▸ HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21570028 1.00 FAP (0.39) FAPOPRK1FURINMAP1LC3BNPY1R
SCHEMBL24898929 1.00 FAP (0.39) FAPOPRK1FURINMAP1LC3BNPY1R
SCHEMBL22702620 1.00 FAP (0.39) FAPOPRK1FURINMAP1LC3BNPY1R
SCHEMBL30483105 1.00 FAP (0.39) FAPOPRK1FURINMAP1LC3BNPY1R
SCHEMBL21570074 0.94 FAP (0.39) FAPOPRK1FURINMAP1LC3BNPY1R
SCHEMBL24224636 0.94 FAP (0.40) FAPOPRK1FURINMAP1LC3BNPY1R
SCHEMBL23943282 0.94 FAP (0.40) FAPOPRK1FURINMAP1LC3BNPY1R
SCHEMBL22138625 0.94 FAP (0.40) FAPOPRK1FURINMAP1LC3BNPY1R
SCHEMBL25450085 0.94 FAP (0.40) FAPOPRK1FURINMAP1LC3BNPY1R
SCHEMBL16946352 0.94 FAP (0.40) FAPOPRK1FURINMAP1LC3BNPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026098621-A1 ENGINEERED ANTIBODY WITH SITE-SPECIFIC CONJUGATION, ANTIBODY-DRUG CONJUGATE, AND APPLICATION THEREOF 百力司康生物医药(杭州)有限公司 2026-05-15 — — WO claimed
US-12605457-B2 Modified EGFR antibody with reduced affinity, drug conjugate, and use thereof Bliss Biopharmaceutical (Hangzhou) Co., Ltd. (CN) 2026-04-21 — — US claimed
US-20240075154-A1 ENGINEERED ANTIBODY, ANTIBODY-DRUG CONJUGATE, AND USE THEREOF BLISS BIOPHARMACEUTICAL HANGZHOU CO LTD (CN) 2024-03-07 — — US claimed
US-20240009318-A1 MODIFIED EGFR ANTIBODY WITH REDUCED AFFINITY, DRUG CONJUGATE, AND USE THEREOF BLISS BIOPHARMACEUTICAL HANGZHOU CO LTD (CN) 2024-01-11 — — US claimed
US-20240002527-A1 ANTI-CD73 ANTIBODY, ANTIBODY-DRUG CONJUGATE, AND USE THEREOF BLISS BIOPHARMACEUTICAL HANGZHOU CO LTD (CN) 2024-01-04 — — US claimed
US-20230414781-A1 ANTI-CD276 ANTIBODY, ANTIBODY-DRUG CONJUGATE, AND USE THEREOF BLISS BIOPHARMACEUTICAL HANGZHOU CO LTD (CN) 2023-12-28 — — US claimed
EP-4247855-A1 ANTI-CD73 ANTIBODY, ANTIBODY-DRUG CONJUGATE, AND USE THEREOF Bliss Biopharmaceutical (Hangzhou) Co., Ltd. (CN) 2023-09-27 — — EP claimed
EP-4247853-A1 MODIFIED EGFR ANTIBODY WITH REDUCED AFFINITY, DRUG CONJUGATE, AND USE THEREOF Bliss Biopharmaceutical (Hangzhou) Co., Ltd. (CN) 2023-09-27 — — EP claimed
EP-4247854-A1 ANTI-CD276 ANTIBODY, ANTIBODY-DRUG CONJUGATE, AND USE THEREOF Bliss Biopharmaceutical (Hangzhou) Co., Ltd. (CN) 2023-09-27 — — EP claimed
EP-4247425-A1 ENGINEERED ANTIBODY, ANTIBODY-DRUG CONJUGATE, AND USE THEREOF Bliss Biopharmaceutical (Hangzhou) Co., Ltd. (CN) 2023-09-27 — — EP claimed
WO-2022105873-A1 ENGINEERED ANTIBODY, ANTIBODY-DRUG CONJUGATE, AND USE THEREOF Bliss Biopharmaceutical (Hangzhou) Co., Ltd. (CN) 2022-05-27 — — WO claimed
WO-2022105881-A1 ANTI-CD73 ANTIBODY, ANTIBODY-DRUG CONJUGATE, AND USE THEREOF Bliss Biopharmaceutical (Hangzhou) Co., Ltd. (CN) 2022-05-27 — — WO claimed
WO-2022105878-A1 MODIFIED EGFR ANTIBODY WITH REDUCED AFFINITY, DRUG CONJUGATE, AND USE THEREOF Bliss Biopharmaceutical (Hangzhou) Co., Ltd. (CN) 2022-05-27 — — WO claimed
WO-2022105879-A1 ANTI-CD276 ANTIBODY, ANTIBODY-DRUG CONJUGATE, AND USE THEREOF Bliss Biopharmaceutical (Hangzhou) Co., Ltd. (CN) 2022-05-27 — — WO claimed
WO-2026098621-A1 ENGINEERED ANTIBODY WITH SITE-SPECIFIC CONJUGATION, ANTIBODY-DRUG CONJUGATE, AND APPLICATION THEREOF 百力司康生物医药(杭州)有限公司 2026-05-15 — — WO disclosed
EP-4727592-A1 CONJUGATED MOLECULES Valink Therapeutics Ltd (GB) 2026-04-22 — — EP disclosed
US-12605457-B2 Modified EGFR antibody with reduced affinity, drug conjugate, and use thereof Bliss Biopharmaceutical (Hangzhou) Co., Ltd. (CN) 2026-04-21 — — US disclosed
US-20190153107-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES ABBVIE INC. (US) 2019-05-23 — — US disclosed
EP-3468993-A1 ANTI-B7-H3 ANTIBODIES AND ANTIBODY DRUG CONJUGATES AbbVie Inc. (US) 2019-04-17 — — EP disclosed
US-20170182179-A1 Antibody Drug Conjugates with Cell Permeable BCL-XL Inhibitors ABBVIE INC. (US) 2017-06-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12605457-B2 Modified EGFR antibody with reduced affinity, drug conjugate, and use thereof EGFR, ERBB2, IGSF11 FAP 4822/4885OPRK1 1663/4885FURIN 4838/4885
US-20170182179-A1 Antibody Drug Conjugates with Cell Permeable BCL-XL Inhibitors BCL2, BCL2L10, BAX FAP 3670/4885OPRK1 4493/4885FURIN 4004/4885
US-20190153107-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES EGFR, ERBB2, ERBB3 FAP 4493/4885OPRK1 3630/4885FURIN 2449/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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