Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.66 |
| ▸ | FBP1 | P09467 | 2/20 | 0.61 |
| ▸ | KDR | P35968 | 3/20 | 0.60 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.60 |
| ▸ | AURKA | O14965 | 1/20 | 0.60 |
| ▸ | INSR | P06213 | 1/20 | 0.60 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.60 |
| ▸ | FLT4 | P35916 | 1/20 | 0.60 |
| ▸ | CLK1 | P49759 | 1/20 | 0.60 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.60 |
| ▸ | TEK | Q02763 | 1/20 | 0.60 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.60 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19124192 | 0.88 | EGFR (0.67) | EGFRFBP1KDRERBB2AURKA | |
| SCHEMBL18660007 | 0.86 | FBP1 (0.82) | EGFRFBP1KDRERBB2AURKA | |
| SCHEMBL19125531 | 0.84 | FBP1 (0.62) | EGFRFBP1KDRERBB2AURKA | |
| SCHEMBL22519385 | 0.83 | EGFR (0.81) | EGFRFBP1KDRERBB2AURKA | |
| SCHEMBL7802281 | 0.80 | EGFR (0.67) | EGFRFBP1KDRERBB2AURKA | |
| SCHEMBL19006863 | 0.79 | EGFR (0.64) | EGFRKDRERBB2 | |
| SCHEMBL18655499 | 0.79 | EGFR (0.85) | EGFRFBP1KDRERBB2AURKA | |
| SCHEMBL22336746 | 0.79 | EGFR (0.94) | EGFRFBP1KDRERBB2AURKA | |
| SCHEMBL23816626 | 0.78 | EGFR (0.65) | EGFRFBP1KDRERBB2AURKA | |
| SCHEMBL18631603 | 0.78 | FBP1 (0.74) | EGFRFBP1KDRERBB2AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3181553-A1 | QUINAZOLINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | Arromax Pharmatech Co., Ltd. (CN) | 2017-06-21 | — | — | EP | disclosed |