Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 3/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17512406 | 0.92 | MAPT (0.49) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL17512408 | 0.88 | MAPT (0.51) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL7150141 | 0.78 | MEN1 (0.57) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL19033236 | 0.77 | NPC1 (0.49) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL3247653 | 0.75 | ALDH1A1 (0.61) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL17512405 | 0.75 | TSHR (0.56) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL6813517 | 0.74 | NPC1 (0.55) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL3245109 | 0.74 | ALDH1A1 (0.60) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL17512436 | 0.74 | MAPT (0.53) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL19033235 | 0.73 | TSHR (0.57) | NPC1RAB9ASMN1; SMN2CASP3SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9688637-B2 | 3-amidobenzamides and uses thereof for increasing cellular levels of A3G and other A3 family members | NORTHWESTERN UNIVERSTIY (US) | 2017-06-27 | — | — | US | disclosed |