Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18352648 | 0.84 | TSHR (0.41) | CHRNB2CHRNA4MAPK1CHRM2CHRM4 | |
| SCHEMBL967608 | 0.84 | — | — | |
| SCHEMBL19814584 | 0.83 | CHRNB2 (0.40) | CHRNB2CHRNA4MAPK1CHRM2CHRM4 | |
| SCHEMBL16250360 | 0.81 | TSHR (0.61) | CHRNB2CHRNA4MAPK1CHRM2CHRM4 | |
| SCHEMBL10821442 | 0.81 | TSHR (0.61) | CHRNB2CHRNA4MAPK1CHRM2CHRM4 | |
| SCHEMBL12054358 | 0.81 | TSHR (0.52) | CHRNB2CHRNA4MAPK1CHRM2CHRM4 | |
| SCHEMBL12780598 | 0.80 | CHRNB2 (0.42) | CHRNB2CHRNA4MAPK1CHRM2CHRM4 | |
| SCHEMBL18355149 | 0.80 | HCAR2 (0.43) | CHRNB2CHRNA4MAPK1CHRM2CHRM4 | |
| SCHEMBL18650145 | 0.79 | CHRNB2 (0.48) | CHRNB2CHRNA4MAPK1CHRM2CHRM4 | |
| SCHEMBL5244737 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9688899-B2 | Curable composition for use as lost circulation material | DOW GLOBAL TECHNOLOGIES LLC (US) | 2017-06-27 | — | — | US | disclosed |