SCHEMBL19035149

SCHEMBL19035149

CC(C)C(=O)C(O)C1CCCC(CC(C)C(=O)C(O)C2CCCNC2)N1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CPN1 P15169 2/20 0.35
CPB2 Q96IY4 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19035148 0.87
SCHEMBL6915115 0.80 CPN1 (0.46) CPN1CPB2
SCHEMBL22504451 0.75
SCHEMBL6913823 0.71 CPN1 (0.34) CPN1CPB2
SCHEMBL9249227 0.66 CA12 (0.33)
SCHEMBL6913506 0.65 SLC6A3 (0.37)
SCHEMBL9287656 0.65 CPN1 (0.49) CPN1CPB2
SCHEMBL18696400 0.65 CPN1 (0.49) CPN1CPB2
SCHEMBL6914144 0.64 GBA1 (0.33)
SCHEMBL19816009 0.63 CPN1 (0.59) CPN1CPB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11117915-B2 Antibacterial aminoglycoside analogs Cipla USA, Inc. (US) 2021-09-14 US disclosed
US-20200317709-A1 ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS Cipla USA, Inc. 2020-10-08 US disclosed
US-9688711-B2 Antibacterial aminoglycoside analogs ACHAOGEN, INC. (US) 2017-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200317709-A1 ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS MRPL21, MRPL9, NQO2 CPN1 4270/4885CPB2 4693/4885
US-11117915-B2 Antibacterial aminoglycoside analogs MRPL21, MRPL9, NQO2 CPN1 4270/4885CPB2 4693/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.