Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1902559 | 0.83 | CETP (0.44) | CETPTSHRLMNA | |
| SCHEMBL1900035 | 0.82 | CETP (0.41) | CETPTSHR | |
| SCHEMBL1899092 | 0.82 | CETP (0.44) | CETPTSHRLMNAKMT2A | |
| SCHEMBL1900918 | 0.79 | CETP (0.62) | CETP | |
| SCHEMBL1897694 | 0.79 | CETP (0.48) | CETPTSHRLMNA | |
| SCHEMBL1900907 | 0.79 | CETP (0.62) | CETP | |
| SCHEMBL5669739 | 0.78 | CETP (0.37) | CETPTSHRLMNAKMT2A | |
| SCHEMBL1896860 | 0.77 | CETP (0.60) | CETP | |
| SCHEMBL1902242 | 0.76 | SLC6A3 (0.38) | TSHRLMNAKMT2A | |
| SCHEMBL1899704 | 0.75 | CETP (0.58) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2316447-A1 | Method of inhibiting remnant lipoprotein production | Japan Tobacco, Inc. (JP) | 2011-05-04 | — | — | EP | claimed |
| EP-2319509-A1 | Method of Inhibiting remnant lipoprotein production | Japan Tobacco, Inc. (JP) | 2011-05-11 | — | — | EP | disclosed |
| EP-2316447-A1 | Method of inhibiting remnant lipoprotein production | Japan Tobacco, Inc. (JP) | 2011-05-04 | — | — | EP | disclosed |