Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 15/20 | 0.48 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | ATAD2 | Q6PL18 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21260604 | 0.93 | BTK (0.45) | BTKBRD4ATAD2 | |
| SCHEMBL17699912 | 0.81 | BTK (0.71) | BTK | |
| SCHEMBL19035389 | 0.79 | BTK (0.44) | BTKBRD4ATAD2EGFR | |
| SCHEMBL28337962 | 0.76 | BTK (0.48) | BTKBRD4ATAD2PDE10A | |
| SCHEMBL20863030 | 0.76 | BTK (0.43) | BTKEGFRDPP4PDE10A | |
| SCHEMBL29782824 | 0.75 | BTK (0.66) | BTK | |
| SCHEMBL17699561 | 0.75 | BTK (0.66) | BTK | |
| SCHEMBL17699651 | 0.75 | BTK (0.66) | BTK | |
| SCHEMBL28165078 | 0.70 | BTK (0.44) | BTKBRD4ATAD2 | |
| SCHEMBL23231160 | 0.70 | BTK (0.40) | BTKBRD4ATAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9688629-B2 | Indole carboxamide compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-06-27 | — | — | US | disclosed |