Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 15/20 | 0.45 |
| ▸ | BRD4 | O60885 | 4/20 | 0.36 |
| ▸ | ATAD2 | Q6PL18 | 4/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19035404 | 0.93 | BTK (0.48) | BTKBRD4ATAD2 | |
| SCHEMBL29782824 | 0.82 | BTK (0.66) | BTK | |
| SCHEMBL17699561 | 0.82 | BTK (0.66) | BTK | |
| SCHEMBL17699651 | 0.82 | BTK (0.66) | BTK | |
| SCHEMBL28165078 | 0.77 | BTK (0.44) | BTKBRD4ATAD2 | |
| SCHEMBL23231160 | 0.77 | BTK (0.40) | BTKBRD4ATAD2HRH4 | |
| SCHEMBL17699912 | 0.75 | BTK (0.71) | BTK | |
| SCHEMBL23231101 | 0.74 | BTK (0.43) | BTKBRD4 | |
| SCHEMBL19035389 | 0.73 | BTK (0.44) | BTKBRD4ATAD2 | |
| SCHEMBL28337962 | 0.70 | BTK (0.48) | BTKBRD4ATAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10604504-B2 | Indole carboxamide compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-03-31 | — | — | US | disclosed |
| US-20190248760-A1 | INDOLE CARBOXAMIDE COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2019-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190248760-A1 | INDOLE CARBOXAMIDE COMPOUNDS | BTK, JAK2, BRD4 | BTK 1/4885BRD4 3/4885ATAD2 2979/4885 |
| US-10604504-B2 | Indole carboxamide compounds | BTK, JAK2, BRD4 | BTK 1/4885BRD4 3/4885ATAD2 2979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.