⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL11721708 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL4143984 | 0.80 | — | — | |
| SCHEMBL2049439 | 0.80 | CYP1A2 (0.34) | — | |
| SCHEMBL132315 | 0.78 | — | — | |
| SCHEMBL19420505 | 0.78 | NAAA (0.37) | — | |
| SCHEMBL531924 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL28375754 | 0.74 | CYP1A2 (0.34) | — | |
| SCHEMBL8643341 | 0.74 | — | — | |
| SCHEMBL5700699 | 0.74 | CYP1A2 (0.31) | — | |
| Hydrochloric Acid SCHEMBL1095481 | 0.72 | CYP1A2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106507794-B | The preparation method of hexichol hydroxyl second mercapto diethylammonium salt base ethyl ester and its hydrochloride and its purposes in medicine | 中国人民解放军军事医学科学院毒物药物研究所 | 2011-07-27 | — | — | CN | claimed |
| US-20260146254-A1 | Enhancing Oligonucleotide Immunomodulatory Activity through Dianophore Long-Lasting Modification: Methods and Applications | SEGENA CORPORATION S.A. (UY) | 2026-05-28 | — | — | US | disclosed |
| EP-4622674-A1 | ENHANCING OLIGONUCLEOTIDE IMMUNOMODULATORY ACTIVITY THROUGH DIANOPHORE LONG-LASTING MODIFICATION: METHODS AND APPLICATIONS | SEGENA CORPORATION S.A. (UY) | 2025-10-01 | — | — | EP | disclosed |
| WO-2024110843-A1 | ENHANCING OLIGONUCLEOTIDE IMMUNOMODULATORY ACTIVITY THROUGH DIANOPHORE LONG-LASTING MODIFICATION: METHODS AND APPLICATIONS | SEGENA CORPORATION S.A. (UY) | 2024-05-30 | — | — | WO | disclosed |
| US-8859615-B2 | Compounds, compositions and methods for reducing toxicity and treating or preventing diseases | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2014-10-14 | — | — | US | disclosed |
| CN-102215840-B | Compounds, compositions and methods for reducing toxicity and treating or preventing diseases | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2014-10-08 | — | — | CN | disclosed |
| US-20110312904-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR REDUCING TOXICITY AND TREATING OR PREVENTING DISEASES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2011-12-22 | — | — | US | disclosed |
| CN-102215840-A | Compounds, compositions and methods for reducing toxicity and treating or preventing diseases | UNIV COLUMBIA | 2011-10-12 | — | — | CN | disclosed |
| CN-106507794-B | The preparation method of hexichol hydroxyl second mercapto diethylammonium salt base ethyl ester and its hydrochloride and its purposes in medicine | 中国人民解放军军事医学科学院毒物药物研究所 | 2011-07-27 | — | — | CN | disclosed |
| EP-2331093-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR REDUCING TOXICITY AND TREATING OR PREVENTING DISEASES | The Trustees of Columbia University in the City of New York (US) | 2011-06-15 | — | — | EP | disclosed |
| US-20110124690-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER OR A NEUROTROPHIC DISORDER | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2011-05-26 | — | — | US | disclosed |
| WO-2010025272-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR REDUCING TOXICITY AND TREATING OR PREVENTING DISEASES | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2010-03-04 | — | — | WO | disclosed |
| WO-2009105123-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING DISEASES | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2009-08-27 | — | — | WO | disclosed |
| WO-2008103916-A2 | COMPOSITIONS AND METHODS FOR TREATING CANCER OR A NEUROTROPHIC DISORDER | THE TRUSTEES OF COLUMBIA UNIVERISTY IN THE CITY OF NEW YORK (US) | 2008-08-28 | — | — | WO | disclosed |
| US-6096727-A | Method for treating wounds using modified hyaluronic acid crosslinked with biscarbodiimide | ANIKA THERAPEUTICS, INC. (US) | 2000-08-01 | — | — | US | disclosed |
| US-6013679-A | REACTING HYALURONIC ACID, OR A SALT, WITH A CARBODIIMIDE TO FORM A WATER INSOLUBLE GEL IN THE ABSENCE OF A NUCLEOPHILE AND A POLYANIONIC POLYSACCHRIDE, DRYING, COMPRESSING TO FORM WATER INSOLUBLE, BIOCOMPATIBLE GEL | ANIKA RESEARCH, INC. (US) | 2000-01-11 | — | — | US | disclosed |
| US-5502081-A | COMPOSITIONS FOR SURGICAL AIDS FORMED FROM REACTION OF CARBODIIMIDE WITH HYALURONIC ACID | RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1996-03-26 | — | — | US | disclosed |
| US-5356883-A | Water-insoluble derivatives of hyaluronic acid and their methods of preparation and use | RESEARCH FOUNDATION OF STATE UNIVERSITY OF N.Y. (US) | 1994-10-18 | — | — | US | disclosed |
| WO-1994002517-A1 | WATER-INSOLUBLE DERIVATIVES OF HYALURONIC ACID AND THEIR METHODS OF PREPARATION AND USE | ANIKA RESEARCH, INC. (US) | 1994-02-03 | — | — | WO | disclosed |
| EP-0416250-A2 | N-acylurea and O-acylisourea derivatives of hyaluronic acid | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1991-03-13 | — | — | EP | disclosed |