SCHEMBL19035994

SCHEMBL19035994

c1ccc(-n2c3ccccc3c3cc(-c4ccc5c(c4)c4cc(-c6cc7c8c(c6)Oc6ccccc6N8c6ccccc6O7)ccc4n5-c4cc5c6c(c4)Oc4ccccc4N6c4ccccc4O5)ccc32)cc1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.42
KDM4E B2RXH2 1/20 0.42
ATM Q13315 1/20 0.42
EDNRA P25101 5/20 0.37
EDNRB P24530 1/20 0.37
PTGER4 P35408 1/20 0.31
ALDH1A1 P00352 2/20 0.31
MEN1 O00255 1/20 0.31
POLB P06746 1/20 0.31
TSHR P16473 1/20 0.31
BRCA1 P38398 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
P2RX4 Q99571 1/20 0.30
TSPO P30536 1/20 0.30
HDAC4 P56524 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19035941 0.98 L3MBTL1 (0.44) L3MBTL1KDM4EATMEDNRAEDNRB
SCHEMBL12333547 0.98 L3MBTL1 (0.44) L3MBTL1KDM4EATMEDNRAEDNRB
SCHEMBL19035979 0.96 EDNRA (0.37) L3MBTL1KDM4EATMEDNRAEDNRB
SCHEMBL19036007 0.96 KDM4E (0.38) L3MBTL1KDM4EATMEDNRAEDNRB
SCHEMBL19009421 0.95 L3MBTL1 (0.42) L3MBTL1KDM4EATMEDNRAEDNRB
SCHEMBL19035973 0.95 L3MBTL1 (0.42) L3MBTL1KDM4EATMEDNRAEDNRB
SCHEMBL19035980 0.95 L3MBTL1 (0.42) L3MBTL1KDM4EATMEDNRAEDNRB
SCHEMBL19035960 0.95 L3MBTL1 (0.42) L3MBTL1KDM4EATMEDNRAEDNRB
SCHEMBL22958756 0.95 L3MBTL1 (0.42) L3MBTL1KDM4EATMEDNRAEDNRB
SCHEMBL19035997 0.95 KDM4E (0.38) L3MBTL1KDM4EATMEDNRAEDNRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10336772-B2 Bicarbazole compound, material for organic light-emitting device including bicarbazole compound, and organic light-emitting device including bicarbazole compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-07-02 US disclosed
US-20170183360-A1 BICARBAZOLE COMPOUND, MATERIAL FOR ORGANIC LIGHT-EMITTING DEVICE INCLUDING BICARBAZOLE COMPOUND, AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING BICARBAZOLE COMPOUND SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-06-29 US disclosed
US-20170183360-A1 BICARBAZOLE COMPOUND, MATERIAL FOR ORGANIC LIGHT-EMITTING DEVICE INCLUDING BICARBAZOLE COMPOUND, AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING BICARBAZOLE COMPOUND SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10336772-B2 Bicarbazole compound, material for organic light-emitting device including bicarbazole compound, and organic light-emitting device including bicarbazole compound BRD1, CYP1B1, ARL1 L3MBTL1 251/4885KDM4E 4064/4885ATM 986/4885
US-20170183360-A1 BICARBAZOLE COMPOUND, MATERIAL FOR ORGANIC LIGHT-EMITTING DEVICE INCLUDING BICARBAZOLE COMPOUND, AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING BICARBAZOLE COMPOUND BRD1, CYP1B1, ARL1 L3MBTL1 251/4885KDM4E 4064/4885ATM 986/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.