Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25317725 | 0.85 | KDM5A (0.46) | SIGMAR1OPRM1OPRK1BCHEKDM4E | |
| SCHEMBL19032646 | 0.84 | CA12 (0.42) | SIGMAR1OPRM1OPRK1BCHE | |
| SCHEMBL29329335 | 0.84 | CA12 (0.42) | SIGMAR1OPRM1OPRK1BCHE | |
| SCHEMBL19040830 | 0.82 | SIGMAR1 (0.48) | SIGMAR1BCHEKDM4ETHRATHRB | |
| SCHEMBL30552770 | 0.80 | SIGMAR1 (0.51) | SIGMAR1BCHEKDM4EHRH3 | |
| SCHEMBL15505725 | 0.78 | SIGMAR1 (0.57) | SIGMAR1BCHEKDM4EALDH1A1 | |
| SCHEMBL2957913 | 0.78 | SIGMAR1 (0.57) | SIGMAR1BCHEKDM4EALDH1A1 | |
| SCHEMBL16269336 | 0.78 | SIGMAR1 (0.57) | SIGMAR1BCHEKDM4EALDH1A1 | |
| SCHEMBL24856252 | 0.77 | SIGMAR1 (0.46) | SIGMAR1BCHEHRH3 | |
| SCHEMBL22642134 | 0.77 | SIGMAR1 (0.49) | SIGMAR1BCHEKDM4EALDH1A1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017112865-A1 | COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF AGENTS | MODERNATX, INC. (US) | 2017-06-29 | — | — | WO | disclosed |