Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.37 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20797245 | 0.95 | HTT (0.56) | TSHRHTTMEN1THRBKMT2A | |
| SCHEMBL21518299 | 0.86 | TSHR (0.54) | TSHRHTTMEN1THRBKMT2A | |
| SCHEMBL28567332 | 0.83 | HTT (0.52) | TSHRHTTMEN1THRBKMT2A | |
| SCHEMBL18126585 | 0.82 | TSHR (0.50) | TSHRHTTMEN1THRBKMT2A | |
| SCHEMBL31417744 | 0.81 | MEN1 (0.38) | TSHRHTTMEN1THRBKMT2A | |
| SCHEMBL10158620 | 0.80 | HTT (0.54) | TSHRHTTMEN1THRBKMT2A | |
| SCHEMBL20054984 | 0.80 | HTT (0.54) | TSHRHTTMEN1THRBKMT2A | |
| SCHEMBL20854580 | 0.80 | CES2 (0.52) | TSHRMEN1THRBKMT2ACES2 | |
| SCHEMBL20854584 | 0.80 | CES2 (0.52) | TSHRMEN1THRBKMT2ACES2 | |
| SCHEMBL20854578 | 0.80 | CES2 (0.52) | TSHRMEN1THRBKMT2ACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017112865-A1 | COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF AGENTS | MODERNATX, INC. (US) | 2017-06-29 | — | — | WO | disclosed |