Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.79 |
| ▸ | HSD17B2 | P37059 | 9/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12491341 | 1.00 | SIGMAR1 (0.79) | SIGMAR1HSD17B2RIPK1L3MBTL1ITGB1 | |
| SCHEMBL11993135 | 0.90 | SIGMAR1 (0.77) | SIGMAR1HSD17B2RIPK1 | |
| SCHEMBL1902449 | 0.88 | SIGMAR1 (1.00) | SIGMAR1HSD17B2RIPK1 | |
| SCHEMBL16134334 | 0.88 | SIGMAR1 (1.00) | SIGMAR1HSD17B2RIPK1 | |
| SCHEMBL12524313 | 0.88 | SIGMAR1 (1.00) | SIGMAR1HSD17B2RIPK1 | |
| SCHEMBL29897574 | 0.88 | SIGMAR1 (1.00) | SIGMAR1HSD17B2RIPK1 | |
| SCHEMBL1901822 | 0.88 | SIGMAR1 (1.00) | SIGMAR1HSD17B2RIPK1 | |
| SCHEMBL12490813 | 0.88 | SIGMAR1 (1.00) | SIGMAR1HSD17B2RIPK1 | |
| SCHEMBL12491087 | 0.84 | SIGMAR1 (0.68) | SIGMAR1 | |
| SCHEMBL1904928 | 0.84 | SIGMAR1 (0.68) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2496555-A1 | 4R,5S-ENANTIOMER OF 2-(5-METHYL-2-OXO-4-PHENYL-PYRROLIDIN-1-YL)-ACETAMIDE WITH NOOTROPIC ACTIVITY | Grindeks, A Joint Stock Company (LV) | 2012-09-12 | — | — | EP | disclosed |
| WO-2011054888-A1 | 4R,5S-ENANTIOMER OF 2-(5-METHYL-2-OXO-4-PHENYL-PYRROLIDIN-1-YL)-ACETAMIDE WITH NOOTROPIC ACTIVITY | GRINDEKS, A JOINT STOCK COMPANY (LV) | 2011-05-12 | — | — | WO | disclosed |