SCHEMBL19044686

SCHEMBL19044686

Cc1c(I)cnc2ccncc12

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 5/20 0.35
MAPK10 P53779 6/20 0.35
DHODH Q02127 1/20 0.34
KDM4E B2RXH2 2/20 0.33
ALDH1A1 P00352 2/20 0.33
ACHE P22303 1/20 0.33
HTT P42858 1/20 0.33
NCOA1 Q15788 1/20 0.33
NCOA3 Q9Y6Q9 1/20 0.33
NPC1 O15118 2/20 0.32
HSP90AA1 P07900 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
HASPIN Q8TF76 1/20 0.32
CCNC P24863 2/20 0.31
CDK8 P49336 2/20 0.31
MEN1 O00255 1/20 0.31
GMNN O75496 1/20 0.31
LMNA P02545 1/20 0.31
NR3C1 P04150 1/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19044149 0.85 KDM4C (0.41) EGFRDHODHKDM4EALDH1A1HTT
SCHEMBL18266931 0.80 CCR1 (0.48) EGFRMAPK10DHODHKDM4EALDH1A1
SCHEMBL19044147 0.76 GPR3 (0.47) KDM4ECYP1A2TOP2A
SCHEMBL21297878 0.74 DHODH (0.41) EGFRMAPK10DHODHKDM4EALDH1A1
SCHEMBL22792739 0.74 EGFR (0.34) EGFRMAPK10DHODHKDM4EALDH1A1
SCHEMBL18574397 0.74 CCNC (0.39) EGFRMAPK10KDM4EHASPINCCNC
SCHEMBL18848328 0.72 CLK1 (0.42) MAPK10KDM4EACHEHTTHASPIN
SCHEMBL15736461 0.72 DHODH (0.46) DHODHKDM4EALDH1A1HTTL3MBTL1
SCHEMBL3147611 0.69 CCR1 (0.46) EGFRKDM4EALDH1A1NPC1L3MBTL1
SCHEMBL27109644 0.69 DHODH (0.43) MAPK10DHODHALDH1A1ACHECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210257559-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2021-08-19 US disclosed
US-10367147-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2019-07-30 US disclosed
US-10312449-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2019-06-04 US disclosed
US-9793487-B2 2017-10-17 US disclosed
US-20170186975-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-29 US disclosed