Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | MAP3K11 | Q16584 | 2/20 | 0.33 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23604276 | 0.86 | CDC14B (0.31) | MAP3K11MAP3K9GABRPGABRDGABRA1 | |
| SCHEMBL24126484 | 0.85 | KMT2A (0.39) | JAK2MEN1CYP2C19KMT2APGR | |
| SCHEMBL31130282 | 0.80 | MEN1 (0.44) | JAK2MEN1CYP2C19KMT2APGR | |
| SCHEMBL22698059 | 0.80 | MEN1 (0.44) | JAK2MEN1CYP2C19KMT2APGR | |
| SCHEMBL5019780 | 0.79 | MEN1 (0.46) | JAK2MEN1CYP2C19KMT2APGR | |
| SCHEMBL29639992 | 0.79 | LPL (0.32) | JAK2 | |
| SCHEMBL21676034 | 0.79 | CDK4 (0.39) | JAK2MAP3K11MAP3K9GABRPGABRD | |
| SCHEMBL26599181 | 0.79 | LPL (0.32) | JAK2 | |
| SCHEMBL29906217 | 0.79 | CDK4 (0.39) | JAK2MAP3K11MAP3K9GABRPGABRD | |
| SCHEMBL22070106 | 0.79 | MEN1 (0.40) | JAK2ZAP70SYKMEN1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3394062-B1 | HETERO-CONDENSED PHENYLQUINAZOLINES AND THEIR USE IN ELECTRONIC DEVICES | IDEMITSU KOSAN CO (JP) | 2019-10-02 | — | — | EP | disclosed |
| WO-2017109727-A1 | HETERO-CONDENSED PHENYLQUINAZOLINES AND THEIR USE IN ELECTRONIC DEVICES | IDEMITSU KOSAN CO., LTD. (JP) | 2017-06-29 | — | — | WO | disclosed |