SCHEMBL19046643

SCHEMBL19046643

c1ccc(-c2nc(-n3c4ccccc4c4c5c6ccccc6c6ccccc6c5c5ccccc5c43)nc3c2ccc2c4ccccc4oc23)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.34
KMT2A Q03164 4/20 0.34
MEN1 O00255 3/20 0.34
CSF1R P07333 1/20 0.34
PDGFRB P09619 1/20 0.34
KIT P10721 1/20 0.34
FLT3 P36888 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
TSHR P16473 5/20 0.33
PTGER1 P34995 1/20 0.32
ADORA2A P29274 1/20 0.32
ALDH1A1 P00352 8/20 0.31
KDM4E B2RXH2 7/20 0.31
HPGD P15428 3/20 0.31
HSD17B10 Q99714 3/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
LMNA P02545 4/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19046693 0.92 MAPT (0.38) MAPTKMT2AMEN1CSF1RPDGFRB
SCHEMBL19758270 0.89 MAPT (0.37) MAPTKMT2AMEN1CSF1RPDGFRB
SCHEMBL19046630 0.88 KDM4E (0.32) MAPTKMT2AMEN1CSF1RPDGFRB
SCHEMBL19046637 0.88 MAPT (0.33) MAPTKMT2AMEN1CSF1RPDGFRB
SCHEMBL19758798 0.86 KDM4E (0.35) MAPTKMT2AMEN1CSF1RPDGFRB
SCHEMBL19986142 0.86 MAPT (0.33) MAPTKMT2AMEN1CSF1RPDGFRB
SCHEMBL19986140 0.85 MAPT (0.38) MAPTKMT2AMEN1CSF1RPDGFRB
SCHEMBL19986143 0.84 MEN1 (0.32) MAPTKMT2AMEN1CSF1RPDGFRB
SCHEMBL19758304 0.84 MEN1 (0.35) MAPTKMT2AMEN1CSF1RPDGFRB
SCHEMBL19758314 0.83 MAPT (0.34) MAPTKMT2AMEN1CSF1RPDGFRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190006601-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICES CONTAINING THEM IDEMITSU KOSAN CO., LTD. (JP) 2019-01-03 US disclosed
WO-2017109722-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICES CONTAINING THEM IDEMITSU KOSAN CO., LTD. (JP) 2017-06-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190006601-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICES CONTAINING THEM SLC39A11, S100A11, SLC29A1 MAPT 2147/4885KMT2A 4037/4885MEN1 967/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.