SCHEMBL19986142

SCHEMBL19986142

c1ccc(-c2nc(-n3c4ccccc4c4c5c6ccccc6c6ccccc6c5c5c6ccccc6oc5c43)nc3c2ccc2ccccc23)cc1

nearest known ligand 0.33

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.33
MEN1 O00255 1/20 0.33
CSF1R P07333 1/20 0.33
PDGFRB P09619 1/20 0.33
KIT P10721 1/20 0.33
FLT3 P36888 1/20 0.33
KMT2A Q03164 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
PTGER1 P34995 1/20 0.32
TSHR P16473 1/20 0.30
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19986143 0.98 MEN1 (0.32) MAPTMEN1CSF1RPDGFRBKIT
SCHEMBL18132431 0.94 MAPT (0.34) MAPTMEN1CSF1RPDGFRBKIT
SCHEMBL19986147 0.93 TDP1 (0.30) TDP1L3MBTL1
SCHEMBL24171787 0.92 MEN1 (0.32) MAPTMEN1CSF1RPDGFRBKIT
SCHEMBL22200008 0.92 MAPT (0.33) MAPTMEN1CSF1RPDGFRBKIT
SCHEMBL22011582 0.89 MEN1 (0.32) MAPTMEN1CSF1RPDGFRBKIT
SCHEMBL19986140 0.88 MAPT (0.38) MAPTMEN1CSF1RPDGFRBKIT
SCHEMBL19046642 0.87 ALDH1A1 (0.35) MAPTMEN1KMT2ATDP1L3MBTL1
SCHEMBL19986098 0.86 ALDH1A1 (0.43) MAPTMEN1CSF1RPDGFRBKIT
SCHEMBL19046643 0.86 MAPT (0.34) MAPTMEN1CSF1RPDGFRBKIT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180083202-A1 COMPOUND FOR ORGANIC OPTOELECTRIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-03-22 US disclosed
US-20180083202-A1 COMPOUND FOR ORGANIC OPTOELECTRIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-03-22 US disclosed