Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 10/20 | 0.59 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 6/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | KDM1B | Q8NB78 | 4/20 | 0.41 |
| ▸ | RCOR1 | Q9UKL0 | 4/20 | 0.41 |
| ▸ | CHKA | P35790 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19047887 | 0.88 | KDM1A (0.58) | KDM1AKDM4EALDH1A1GAAMAPT | |
| SCHEMBL19047889 | 0.86 | KDM1A (0.59) | KDM1AKDM4EALDH1A1GAAMAPT | |
| SCHEMBL13438629 | 0.80 | HDAC3 (0.51) | KDM1AADRA2CKDM4EALDH1A1GAA | |
| SCHEMBL11934741 | 0.80 | HDAC3 (0.51) | KDM1AADRA2CKDM4EALDH1A1GAA | |
| SCHEMBL20134666 | 0.78 | KDM1A (0.57) | KDM1AALDH1A1MAPTKMT2AHTR7 | |
| SCHEMBL19047563 | 0.77 | KDM1A (0.62) | KDM1A | |
| SCHEMBL20134649 | 0.77 | KDM1A (0.59) | KDM1AMAPT | |
| SCHEMBL13905999 | 0.76 | HDAC3 (0.55) | KDM1AADRA2CKDM4EALDH1A1GAA | |
| SCHEMBL19025265 | 0.75 | KDM1A (1.00) | KDM1A | |
| SCHEMBL19047906 | 0.74 | KDM1A (0.62) | KDM1AALDH1A1MAPTMAOBGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9809541-B2 | LSD1 inhibitors | Mirati Therapeutics, Inc. (US) | 2017-11-07 | — | — | US | disclosed |
| US-20170183308-A1 | LSD1 Inhibitors | Mirati Therapeutics, Inc. (US) | 2017-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170183308-A1 | LSD1 Inhibitors | KDM1B, KDM1A, KDM3A | KDM1A 2/4885ADRA2C 3700/4885KDM4E 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.