SCHEMBL19048837

SCHEMBL19048837

c1ccc(-c2ccccc2Nc2ccc(-c3ccc(N(c4ccccc4)c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP3 P05413 1/20 0.42
FABP4 P15090 1/20 0.42
FABP5 Q01469 1/20 0.42
MAPK13 O15264 1/20 0.40
MAPK12 P53778 1/20 0.40
MAPK11 Q15759 1/20 0.40
MAPK14 Q16539 1/20 0.40
AURKA O14965 1/20 0.39
AKR1C3 P42330 1/20 0.38
KDM1A O60341 2/20 0.37
ALDH1A1 P00352 5/20 0.37
KDM4E B2RXH2 3/20 0.37
MAPT P10636 3/20 0.37
CYP1A2 P05177 3/20 0.37
CYP2D6 P10635 3/20 0.37
CYP2C19 P33261 3/20 0.37
TDP1 Q9NUW8 2/20 0.37
CYP2C9 P11712 2/20 0.37
CYP3A4 P08684 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20736551 1.00 FABP3 (0.42) FABP3FABP4FABP5MAPK13MAPK12
SCHEMBL12933993 0.98 FABP3 (0.40) FABP3FABP4FABP5MAPK13MAPK12
SCHEMBL16905782 0.98 FABP3 (0.44) FABP3FABP4FABP5MAPK13MAPK12
SCHEMBL919631 0.95 FABP3 (0.46) FABP3FABP4FABP5MAPK13MAPK12
SCHEMBL4098527 0.93 MAPT (0.42) FABP3FABP4FABP5MAPK13MAPK12
SCHEMBL17383359 0.93 FABP3 (0.38) FABP3FABP4FABP5MAPK13MAPK12
SCHEMBL14345522 0.91 NR3C2 (0.42) FABP3FABP4FABP5MAPK13MAPK12
SCHEMBL18057676 0.90 PTGER4 (0.36) FABP3FABP4FABP5MAPK13MAPK12
SCHEMBL10180995 0.90 ALDH1A1 (0.42) FABP4AKR1C3KDM1AALDH1A1KDM4E
SCHEMBL19022543 0.88 MEN1 (0.38) FABP3FABP4FABP5MAPK13MAPK12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3185331-A1 ORGANIC LIGHT-EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2017-06-28 EP disclosed