Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 6/20 | 0.71 |
| ▸ | PDE7B | Q9NP56 | 3/20 | 0.71 |
| ▸ | MAPT | P10636 | 7/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.54 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.54 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.51 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.51 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25250134 | 0.89 | PDE7A (0.66) | PDE7APDE7BMAPTMEN1KMT2A | |
| SCHEMBL6039967 | 0.85 | TXNRD1 (0.74) | PDE7APDE7BMAPTMEN1KMT2A | |
| SCHEMBL19048781 | 0.84 | MAPT (0.62) | PDE7APDE7BMAPTMEN1KMT2A | |
| SCHEMBL2968510 | 0.83 | PDE7A (0.68) | PDE7APDE7BMAPTMEN1KMT2A | |
| SCHEMBL2968440 | 0.83 | PDE7A (0.68) | PDE7APDE7BMAPTMEN1KMT2A | |
| SCHEMBL29217093 | 0.83 | PDE7A (0.68) | PDE7APDE7BMAPTMEN1KMT2A | |
| SCHEMBL8884363 | 0.83 | PDE7A (1.00) | PDE7APDE7BMAPTMEN1KMT2A | |
| SCHEMBL810289 | 0.83 | PDE7A (0.68) | PDE7APDE7BMAPTMEN1KMT2A | |
| SCHEMBL6743647 | 0.83 | PDE7A (0.73) | PDE7APDE7BMAPTMEN1KMT2A | |
| SCHEMBL1713219 | 0.82 | PDE7A (0.65) | PDE7APDE7BMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113968838-B | Thiobenzopyran compound and application thereof in treatment of rheumatoid arthritis | 华创合成制药股份有限公司 | 2024-04-02 | — | — | CN | disclosed |
| EP-3184509-A1 | COMPOUNDS FOR THE DETECTION, CAPTURE AND/OR SEPARATION OF POLLUTING GASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2017-06-28 | — | — | EP | disclosed |