SCHEMBL19049986

SCHEMBL19049986

CNc1nc(Cl)nc2c1ncn2C1CCCCO1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
YTHDC1 Q96MU7 3/20 1.00
ADORA3 P0DMS8 8/20 0.57
ADORA2A P29274 2/20 0.52
ADORA1 P30542 1/20 0.52
CYP2C19 P33261 1/20 0.51
FLT3 P36888 2/20 0.48
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
HTR2C P28335 1/20 0.47
HTR2B P41595 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17902901 0.88 YTHDC1 (0.79) YTHDC1ADORA3ADORA2AADORA1CYP2C19
SCHEMBL1713275 0.88 YTHDC1 (0.79) YTHDC1ADORA3ADORA2AADORA1CYP2C19
SCHEMBL5442351 0.87 YTHDC1 (0.78) YTHDC1ADORA3ADORA2AADORA1CYP2C19
SCHEMBL2709647 0.87 YTHDC1 (0.77) YTHDC1ADORA3ADORA2AADORA1
SCHEMBL16549238 0.87 YTHDC1 (0.77) YTHDC1ADORA3ADORA2AADORA1
SCHEMBL2943022 0.87 YTHDC1 (0.77) YTHDC1ADORA3ADORA2AADORA1
SCHEMBL2709651 0.87 YTHDC1 (0.77) YTHDC1ADORA3ADORA2AADORA1
SCHEMBL5447191 0.86 YTHDC1 (0.76) YTHDC1ADORA3ADORA2AADORA1
SCHEMBL17902888 0.86 YTHDC1 (0.76) YTHDC1ADORA3ADORA2AADORA1
SCHEMBL2945927 0.86 YTHDC1 (0.76) YTHDC1ADORA3ADORA2AADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024105159-A1 LIGANDS OF THE M6A-RNA READERS UNIVERSITY OF ZURICH (CH) 2024-05-23 WO disclosed
EP-2320905-B1 NOVEL ADENINE DERIVATIVES GLAXOSMITHKLINE LLC (US) 2017-06-28 EP disclosed