Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15998100 | 1.00 | MAPT (0.43) | MAPTALDH1A1POLBGAAMEN1 | |
| SCHEMBL12557559 | 0.89 | ALDH1A1 (0.53) | MAPTALDH1A1POLBGAAMEN1 | |
| SCHEMBL12548139 | 0.89 | ALDH1A1 (0.53) | MAPTALDH1A1POLBGAAMEN1 | |
| SCHEMBL30462193 | 0.89 | ALDH1A1 (0.53) | MAPTALDH1A1POLBGAAMEN1 | |
| SCHEMBL19241993 | 0.87 | ALDH1A1 (0.43) | MAPTALDH1A1POLBGAAMEN1 | |
| SCHEMBL19563400 | 0.85 | ALDH1A1 (0.48) | MAPTALDH1A1POLBGAAMEN1 | |
| SCHEMBL25419498 | 0.85 | MAPT (0.50) | MAPTALDH1A1POLBGAAMEN1 | |
| SCHEMBL5355218 | 0.85 | MAPT (0.50) | MAPTALDH1A1POLBGAAMEN1 | |
| SCHEMBL14516729 | 0.85 | MAPT (0.50) | MAPTALDH1A1POLBGAAMEN1 | |
| SCHEMBL15998110 | 0.84 | ALDH1A1 (0.47) | MAPTALDH1A1POLBGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2316974-B2 | Dark quenchers for donor-acceptor energy transfer | BIOSEARCH TECH INC (US) | 2017-06-28 | — | — | EP | disclosed |