Propylene Oxide

Propylene Oxide

SCHEMBL1905554

C=CCC(OC(CC=C)C1CO1)C1CO1.CC1CO1

nearest known ligand 0.31

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3402458 0.92 TDP1 (0.35) ALDH1A1TDP1
SCHEMBL26629 0.92 TDP1 (0.35) ALDH1A1TDP1
Oxirane SCHEMBL6300592 0.86 ALDH1A1 (0.31) ALDH1A1TDP1
Ethylene Glycol SCHEMBL5922937 0.85 ALDH1A1 (0.31) ALDH1A1TDP1
SCHEMBL728660 0.84
Methacrylic Acid SCHEMBL6533344 0.80 ALDH1A1 (0.36) ALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL5922803 0.79 TSHR (0.33) ALDH1A1
Triethylene Glycol SCHEMBL5922883 0.78 MEN1 (0.35) ALDH1A1
SCHEMBL6466036 0.76
SCHEMBL32679905 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150191607-A1 Anti-fouling Paints and Coatings REACTIVE SURFACES, LTD (US) 2015-07-09 US disclosed
US-20140196631-A1 VISUAL ASSAYS FOR COATINGS INCORPORATING BIOACTIVE ENZYMES FOR CATALYTIC FUNCTIONS REACTIVE SURFACE, LTD. (US) 2014-07-17 US disclosed
US-20120097194-A1 Polymeric Coatings Incorporating Bioactive Enzymes for Catalytic Function REACTIVE SURFACES, LTD. (US) 2012-04-26 US disclosed
US-20110250626-A1 Visual Assays for Coatings Incorporating Bioactive Enzymes for Catalytic Functions REACTIVE SURFACES, LTD. (US) 2011-10-13 US disclosed
US-20110240064-A1 Polymeric Coatings Incorporating Bioactive Enzymes for Cleaning a Surface REACTIVE SURFACES, LTD. (US) 2011-10-06 US disclosed
EP-2324087-A2 COATINGS AND SURFACE TREATMENTS HAVING ACTIVE ENZYMES AND PEPTIDES McDaniel, Steven C. (US) 2011-05-25 EP disclosed
US-20100233146-A1 Coatings and Surface Treatments Having Active Enzymes and Peptides REACTIVE SURFACES, LTD. (US) 2010-09-16 US disclosed
US-20100210745-A1 Molecular Healing of Polymeric Materials, Coatings, Plastics, Elastomers, Composites, Laminates, Adhesives, and Sealants by Active Enzymes REACTIVE SURFACES, LTD. (US) 2010-08-19 US disclosed
WO-2009155115-A2 COATINGS AND SURFACE TREATMENTS HAVING ACTIVE ENZYMES AND PEPTIDES REACTIVE SURFACES, LTD. (US) 2009-12-23 WO disclosed
EP-1378534-B1 Poly(arylene ether)-containing thermoset composition GEN ELECTRIC (US) 2007-07-18 EP disclosed
US-20060207930-A1 Interfacial composite structure and method of making them GENERAL ELECTRIC COMPANY 2006-09-21 US disclosed
US-6812276-B2 CURABLE MIXTURE OF A FUNCTIONALIZED POLY(ARYLENE ETHER) SUCH AS METHACRYLATE-ENDCAPPED POLY(2,6-DIMETHYLPHENYL ETHER), AN ALKENYL AROMATIC MONOMER, AND AN ALKOXYLATED ACRYLOYL MONOMER; GOOD STIFFNESS, TOUGHNESS, AND HEAT RESISTANCE GENERAL ELECTRIC COMPANY 2004-11-02 US disclosed
EP-1378534-A1 Poly(arylene ether)-containing thermoset composition GENERAL ELECTRIC COMPANY (US) 2004-01-07 EP disclosed
US-6627704-B2 Blend of polyphenylene ether, styrene compound and acrylic ester GENERAL ELECTRIC COMPANY 2003-09-30 US disclosed
US-20030096123-A1 Curable mixture of a functionalized poly(arylene ether) such as methacrylate-endcapped poly(2,6-dimethylphenyl ether), an alkenyl aromatic monomer, and an alkoxylated acryloyl monomer; good stiffness, toughness, and heat resistance GENERAL ELECTRIC COMPANY 2003-05-22 US disclosed
US-20010053820-A1 Poly(arylene ether)-containing thermoset composition, method for the preparation thereof, and articles derived therefrom SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2001-12-20 US disclosed