Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 4/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 2/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.39 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | MASP2 | O00187 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | FCER2 | P06734 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1901449 | 1.00 | KLKB1 (0.42) | KLKB1PSMB5PSMB8LCKPDPK1 | |
| SCHEMBL1901817 | 0.88 | KLKB1 (0.49) | KLKB1PSMB5PDPK1PSMB1PSMB2 | |
| SCHEMBL1901814 | 0.88 | KLKB1 (0.49) | KLKB1PSMB5PDPK1PSMB1PSMB2 | |
| SCHEMBL1904352 | 0.85 | KLKB1 (0.46) | KLKB1PSMB5PSMB8PDPK1PSMB1 | |
| SCHEMBL1904349 | 0.85 | KLKB1 (0.46) | KLKB1PSMB5PSMB8PDPK1PSMB1 | |
| SCHEMBL1905072 | 0.85 | NAMPT (0.46) | KLKB1PSMB5PDPK1PSMB1PSMB2 | |
| SCHEMBL1903988 | 0.85 | NAMPT (0.46) | KLKB1PSMB5PDPK1PSMB1PSMB2 | |
| SCHEMBL1906121 | 0.85 | KLKB1 (0.43) | KLKB1PSMB5PDPK1PSMB1PSMB2 | |
| Trifluoroacetic Acid SCHEMBL1908460 | 0.84 | KLKB1 (0.47) | KLKB1PSMB5PDPK1PSMB1PSMB2 | |
| SCHEMBL1901348 | 0.84 | KLKB1 (0.42) | KLKB1PSMB5PDPK1PSMB1PSMB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051671-A1 | AMINOPYRIDINE DERIVATIVES AS KALLIKREIN INHIBITORS | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | claimed |