Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 9/20 | 0.45 |
| ▸ | SMARCA4 | P51532 | 8/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | LOX | P28300 | 1/20 | 0.40 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4635970 | 0.85 | SMARCA2 (0.47) | SMARCA2SMARCA4RECQLLOXLOXL3 | |
| SCHEMBL17233219 | 0.83 | SMARCA2 (0.45) | SMARCA2SMARCA4RECQLLOXLOXL3 | |
| SCHEMBL19030966 | 0.81 | LOX (0.48) | SMARCA2SMARCA4RECQLLOXLOXL3 | |
| SCHEMBL14101817 | 0.81 | RECQL (0.48) | SMARCA2SMARCA4RECQLLOXLOXL3 | |
| SCHEMBL24615889 | 0.81 | ALDH1A1 (0.48) | SMARCA2SMARCA4 | |
| SCHEMBL11454686 | 0.81 | HRH3 (0.46) | SMARCA2SMARCA4 | |
| SCHEMBL21608361 | 0.79 | SMARCA2 (0.47) | SMARCA2SMARCA4RECQLLOXLOXL3 | |
| SCHEMBL1419548 | 0.78 | AR (0.49) | ABL1AR | |
| SCHEMBL12764425 | 0.76 | ESR1 (0.44) | SMARCA2SMARCA4RECQLLOXLOXL3 | |
| SCHEMBL10502486 | 0.76 | SMARCA2 (0.62) | SMARCA2SMARCA4PIK3CAMAPK8MAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017109027-A1 | IMPROVED PROCESS FOR MAKING CROTONYLAMINOPYRIDINES | INTERVET INTERNATIONAL B.V. (NL) | 2017-06-29 | — | — | WO | disclosed |