Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PI4KA | P42356 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | BCR | P11274 | 1/20 | 0.31 |
| ▸ | WNT3A | P56704 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.31 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19062436 | 1.00 | PIK3CD (0.35) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG | |
| SCHEMBL20026213 | 1.00 | PIK3CD (0.35) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG | |
| SCHEMBL20026327 | 0.85 | MKNK1 (0.46) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG | |
| SCHEMBL20026168 | 0.85 | MKNK1 (0.31) | — | |
| SCHEMBL20026159 | 0.84 | MAPT (0.36) | — | |
| SCHEMBL19062432 | 0.83 | PIK3CA (0.39) | PIK3CDPIK3CAPIK3CBPI4KAPI4KB | |
| SCHEMBL20026088 | 0.83 | PIK3CA (0.39) | PIK3CDPIK3CAPIK3CBPI4KAPI4KB | |
| SCHEMBL19062805 | 0.82 | CYP2A6 (0.44) | — | |
| SCHEMBL14024065 | 0.82 | CYP2A6 (0.44) | — | |
| SCHEMBL14024887 | 0.82 | SCN10A (0.43) | PIK3CDPIK3CAPIK3CBPI4KBPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1934238-B1 | TRIAZOLE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | MELINTA THERAPEUTICS INC (US) | 2017-06-28 | — | — | EP | disclosed |