Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | PI4KA | P42356 | 2/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | F9 | P00740 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.30 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19062432 | 1.00 | PIK3CA (0.39) | PIK3CAPI4KAPI4KBTLR9TLR8 | |
| SCHEMBL20026168 | 0.84 | MKNK1 (0.31) | MKNK1MKNK2 | |
| SCHEMBL19063237 | 0.83 | PIK3CD (0.35) | PIK3CAPI4KAPI4KBPIK3CDPIK3CB | |
| SCHEMBL20026213 | 0.83 | PIK3CD (0.35) | PIK3CAPI4KAPI4KBPIK3CDPIK3CB | |
| SCHEMBL19062436 | 0.83 | PIK3CD (0.35) | PIK3CAPI4KAPI4KBPIK3CDPIK3CB | |
| SCHEMBL20026327 | 0.82 | MKNK1 (0.46) | PIK3CAPI4KAPI4KBKCNH2PIK3CD | |
| SCHEMBL14023915 | 0.81 | PIK3CA (0.39) | PIK3CAPI4KAPI4KBTLR9TLR8 | |
| SCHEMBL20026159 | 0.81 | MAPT (0.36) | — | |
| SCHEMBL20026348 | 0.81 | ERN1 (0.33) | MKNK1MKNK2 | |
| SCHEMBL13527559 | 0.79 | PIK3CA (0.33) | PIK3CAPI4KAPI4KBTLR9TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180094016-A1 | Triazole Compounds And Methods Of Making And Using The Same | BioVersys AG (CH) | 2018-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180094016-A1 | Triazole Compounds And Methods Of Making And Using The Same | IL33, PROKR1, VIP | PIK3CA 3581/4885PI4KA 2535/4885PI4KB 2180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.