Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.36 |
| ▸ | S100A4 | P26447 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | CCKAR | P32238 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1906364 | 1.00 | PTGDR2 (0.42) | PTGDR2TP53MTNR1AMTNR1BS100A4 | |
| SCHEMBL1901537 | 0.94 | PTGDR2 (0.41) | PTGDR2TP53MTNR1AMTNR1BRXFP1 | |
| SCHEMBL1901536 | 0.94 | PTGDR2 (0.41) | PTGDR2TP53MTNR1AMTNR1BRXFP1 | |
| SCHEMBL1902936 | 0.94 | PTGDR2 (0.41) | PTGDR2TP53MTNR1AMTNR1BRXFP1 | |
| SCHEMBL1902934 | 0.94 | PTGDR2 (0.41) | PTGDR2TP53MTNR1AMTNR1BRXFP1 | |
| SCHEMBL1905495 | 0.92 | PTGDR2 (0.43) | PTGDR2TP53MTNR1AMTNR1BNPC1 | |
| SCHEMBL1905496 | 0.92 | PTGDR2 (0.43) | PTGDR2TP53MTNR1AMTNR1BNPC1 | |
| SCHEMBL1900836 | 0.92 | MTNR1A (0.43) | PTGDR2MTNR1AMTNR1BNPC1POLB | |
| SCHEMBL1900833 | 0.92 | MTNR1A (0.43) | PTGDR2MTNR1AMTNR1BNPC1POLB | |
| SCHEMBL1905000 | 0.89 | PTGDR2 (0.51) | PTGDR2TP53MTNR1AMTNR1BRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2051962-B1 | (3-AMINO-1,2,3,4-TETRAHYDRO-9H-CARBAZOL-9-YL)-ACETIC ACID DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2011-10-26 | — | — | EP | disclosed |
| EP-2316824-A1 | (3-Amino-1,2,3,4-tetrahydro-9H-carbazoI-9-yl)-acetic acid derivates | Actelion Pharmaceuticals Ltd. (CH) | 2011-05-04 | — | — | EP | disclosed |