SCHEMBL19065738

SCHEMBL19065738

C[Si](C)(C)Cc1ccc(Br)cc1

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.58
TAAR1 Q96RJ0 3/20 0.43
HTR2A P28223 1/20 0.42
CYP2A6 P11509 1/20 0.42
IDO1 P14902 2/20 0.41
ALDH1A1 P00352 1/20 0.39
PYCR1 P32322 3/20 0.39
EPHX2 P34913 1/20 0.38
MAOB P27338 1/20 0.36
CYP19A1 P11511 1/20 0.36
CYP11B1 P15538 1/20 0.36
CYP11B2 P19099 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3949041 0.86 ESR1 (0.74) ESR1IDO1ALDH1A1
SCHEMBL6154086 0.80 TAAR1 (0.40) ESR1TAAR1HTR2ACYP2A6IDO1
SCHEMBL986310 0.76 ESR1 (0.61) ESR1TAAR1CYP2A6IDO1ALDH1A1
SCHEMBL20004512 0.75 TAAR1 (0.50) TAAR1HTR2ACYP2A6IDO1EPHX2
SCHEMBL19064379 0.74 ESR1 (0.58) ESR1TAAR1IDO1ALDH1A1
SCHEMBL2007156 0.74 ESR1 (0.58) ESR1ALDH1A1MAOBCYP19A1CYP11B1
SCHEMBL5485087 0.74 TAAR1 (0.42) TAAR1HTR2ACYP2A6IDO1ALDH1A1
SCHEMBL10712863 0.74 ESR1 (1.00) ESR1TAAR1IDO1ALDH1A1
SCHEMBL18694997 0.74 ESR1 (0.58) ESR1
SCHEMBL17529742 0.73 TAAR1 (0.43) TAAR1HTR2ACYP2A6IDO1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118895051-A Industrial ageing-resistant rubber compound and preparation method thereof 温州合丰胶业股份有限公司 2024-11-05 CN claimed
CN-118834391-A Flame-resistant and radiation-resistant methyl vinyl silicone rubber and preparation method thereof 温州合丰胶业股份有限公司 2024-10-25 CN claimed
US-20250326936-A1 ARTICLES INCLUDING SURFACE COATINGS AND METHODS TO PRODUCE THEM MAXTERIAL INC (US) 2025-10-23 US disclosed
US-12173166-B2 Articles including surface coatings and methods to produce them MAXTERIAL, INC. (US) 2024-12-24 US disclosed
CN-118895051-A Industrial ageing-resistant rubber compound and preparation method thereof 温州合丰胶业股份有限公司 2024-11-05 CN disclosed
CN-118834391-A Flame-resistant and radiation-resistant methyl vinyl silicone rubber and preparation method thereof 温州合丰胶业股份有限公司 2024-10-25 CN disclosed
CN-118834391-A Flame-resistant and radiation-resistant methyl vinyl silicone rubber and preparation method thereof 温州合丰胶业股份有限公司 2024-10-25 CN disclosed
US-20230295827-A1 COATINGS AND COATED SURFACES INCLUDING LOW-SURFACE ENERGY INORGANIC PARTICLES MAXTERIAL INC (US) 2023-09-21 US disclosed
US-11542621-B1 Coatings and coated surfaces including low-surface energy inorganic particles MAXTERIAL, INC. (US) 2023-01-03 US disclosed
EP-3691894-A1 ARTICLES INCLUDING SURFACE COATINGS AND METHODS TO PRODUCE THEM Maxterial, Inc. (US) 2020-08-12 EP disclosed
CN-111405980-A Article comprising a surface coating and method for producing the same 麦克斯特里尔有限公司 2020-07-10 CN disclosed
US-20190186035-A1 ARTICLES INCLUDING SURFACE COATINGS AND METHODS TO PRODUCE THEM MAXTERIAL INC (US) 2019-06-20 US disclosed
WO-2019067950-A1 ARTICLES INCLUDING SURFACE COATINGS AND METHODS TO PRODUCE THEM MAXTERIAL, INC. (US) 2019-04-04 WO disclosed
EP-3397788-A1 COATINGS AND COATED SURFACES WITH SELECTED SURFACE CHARACTERISTICS AND FEATURES Maxterial, Inc. (US) 2018-11-07 EP disclosed
US-20180028029-A1 DRYING APPARATUS COMPRISING A HYDROPHOBIC MATERIAL HAGHDOOST ATIEH (US) 2018-02-01 US disclosed
US-20170334170-A1 ARTICLES INCLUDING ADHESION ENHANCING COATINGS AND METHODS OF PRODUCING THEM HAGHDOOST ATIEH (US) 2017-11-23 US disclosed
US-20170190139-A1 COATINGS AND COATED SURFACES WITH SELECTED SURFACE CHARACTERISTICS AND FEATURES HAGHDOOST ATIEH (US) 2017-07-06 US disclosed