Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 4/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | PYCR1 | P32322 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4450244 | 0.86 | ESR1 (0.38) | IDO1 | |
| SCHEMBL2687231 | 0.78 | HRH3 (0.41) | TAAR1CYP2A6CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL7557619 | 0.76 | CA1 (0.39) | — | |
| SCHEMBL1479279 | 0.76 | IDO1 (0.48) | TAAR1HTR2ACYP2A6IDO1CYP19A1 | |
| SCHEMBL5488977 | 0.75 | TAAR1 (0.50) | TAAR1HTR2ACYP2A6IDO1CYP19A1 | |
| SCHEMBL19065738 | 0.74 | ESR1 (0.58) | TAAR1HTR2ACYP2A6IDO1CYP19A1 | |
| SCHEMBL5484080 | 0.74 | IDO1 (0.46) | TAAR1CYP2A6IDO1CYP19A1CYP11B1 | |
| SCHEMBL2684489 | 0.74 | IDO1 (0.46) | TAAR1IDO1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL5552238 | 0.74 | ESR1 (0.31) | — | |
| SCHEMBL242725 | 0.72 | CALM1 (0.45) | TAAR1HTR2ACYP2A6IDO1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |