Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LCLAT1 | Q6UWP7 | 4/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19066431 | 0.93 | LCLAT1 (0.35) | KMT2ATSHRADORA2ALMNALCLAT1 | |
| SCHEMBL24297149 | 0.92 | KMT2A (0.35) | KMT2AMEN1TSHRADORA2ALCLAT1 | |
| SCHEMBL19066439 | 0.88 | KCNA5 (0.38) | KCNA5KCNH2KCNB1KMT2AMEN1 | |
| Difamilast SCHEMBL4275421 | 0.88 | HPGD (0.44) | KCNA5KCNH2KCNB1KMT2AMEN1 | |
| Difamilast SCHEMBL29372760 | 0.88 | HPGD (0.44) | KCNA5KCNH2KCNB1KMT2AMEN1 | |
| SCHEMBL4276921 | 0.88 | HPGD (0.44) | KCNA5KCNH2KCNB1KMT2AMEN1 | |
| Difamilast SCHEMBL30978541 | 0.88 | HPGD (0.44) | KCNA5KCNH2KCNB1KMT2AMEN1 | |
| SCHEMBL22059375 | 0.87 | LCLAT1 (0.39) | KMT2AMEN1TSHRADORA2AADORA1 | |
| SCHEMBL31239126 | 0.86 | LCLAT1 (0.37) | KCNA5KCNH2KCNB1KMT2ATSHR | |
| SCHEMBL19066440 | 0.86 | LCLAT1 (0.37) | KCNA5KCNH2KCNB1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240366573-A1 | OINTMENT CONTAINING AN OXAZOLE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2024-11-07 | — | — | US | disclosed |
| US-20220117944-A1 | OINTMENT CONTAINING AN OXAZOLE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2022-04-21 | — | — | US | disclosed |
| US-20220117944-A1 | OINTMENT CONTAINING AN OXAZOLE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2022-04-21 | — | — | US | disclosed |
| US-20200171006-A1 | OINTMENT CONTAINING AN OXAZOLE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-06-04 | — | — | US | disclosed |
| US-20200171006-A1 | OINTMENT CONTAINING AN OXAZOLE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-06-04 | — | — | US | disclosed |
| US-10588893-B2 | Ointment containing an oxazole compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-03-17 | — | — | US | disclosed |
| US-10588893-B2 | Ointment containing an oxazole compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-03-17 | — | — | US | disclosed |
| US-20190000810-A1 | OINTMENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2019-01-03 | — | — | US | disclosed |
| US-20190000810-A1 | OINTMENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2019-01-03 | — | — | US | disclosed |
| EP-3397619-A1 | OINTMENT | Otsuka Pharmaceutical Co., Ltd. (JP) | 2018-11-07 | — | — | EP | disclosed |
| WO-2017115780-A1 | OINTMENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2017-07-06 | — | — | WO | disclosed |
| WO-2017115780-A1 | OINTMENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2017-07-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240366573-A1 | OINTMENT CONTAINING AN OXAZOLE COMPOUND | PDE12, PDE4B, PDE4A | KCNA5 2403/4885KCNH2 3365/4885KCNB1 3004/4885 |
| US-20200171006-A1 | OINTMENT CONTAINING AN OXAZOLE COMPOUND | PDE12, PDE4B, PDE4A | KCNA5 2403/4885KCNH2 3365/4885KCNB1 3004/4885 |
| US-20220117944-A1 | OINTMENT CONTAINING AN OXAZOLE COMPOUND | PDE12, PDE4B, PDE4A | KCNA5 2403/4885KCNH2 3365/4885KCNB1 3004/4885 |
| US-10588893-B2 | Ointment containing an oxazole compound | PDE12, PDE4B, PDE4A | KCNA5 2403/4885KCNH2 3365/4885KCNB1 3004/4885 |
| US-20190000810-A1 | OINTMENT | PDE12, PDE4B, PDE4A | KCNA5 3117/4885KCNH2 3772/4885KCNB1 3422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.