Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.72 |
| ▸ | MAPT | P10636 | 4/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.72 |
| ▸ | RORC | P51449 | 9/20 | 0.71 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.63 |
| ▸ | PPIA | P62937 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19066466 | 0.90 | SMN1; SMN2 (0.69) | SMN1; SMN2MAPTLMNAALDH1A1TDP1 | |
| SCHEMBL7120590 | 0.87 | RORC (0.78) | SMN1; SMN2MAPTLMNAALDH1A1TDP1 | |
| SCHEMBL19066460 | 0.84 | MAPT (1.00) | SMN1; SMN2MAPTLMNAALDH1A1TDP1 | |
| SCHEMBL19066459 | 0.83 | MEN1 (0.68) | SMN1; SMN2MAPTLMNAALDH1A1TDP1 | |
| SCHEMBL19066461 | 0.82 | RORC (0.70) | SMN1; SMN2MAPTLMNAALDH1A1TDP1 | |
| SCHEMBL13297762 | 0.81 | CYP19A1 (0.67) | SMN1; SMN2MAPTLMNAALDH1A1TDP1 | |
| SCHEMBL18146442 | 0.80 | RORC (0.81) | SMN1; SMN2MAPTLMNAALDH1A1TDP1 | |
| SCHEMBL13297753 | 0.80 | CYP19A1 (0.64) | SMN1; SMN2MAPTLMNAALDH1A1CYP19A1 | |
| SCHEMBL38661589 | 0.79 | MEN1 (0.66) | MAPTLMNAALDH1A1CYP19A1PPIA | |
| SCHEMBL13297761 | 0.79 | CYP19A1 (0.77) | MAPTLMNAALDH1A1CYP19A1PPIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017115914-A1 | PPARγ PHOSPHORYLATION INHIBITOR AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 서울대학교산학협력단 | 2017-07-06 | — | — | WO | disclosed |