Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | GFER | P55789 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 7/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16480344 | 0.90 | KDM4E (0.55) | KDM4EMAPTLMNAHTTHPGD | |
| SCHEMBL19072010 | 0.88 | KDM4E (0.40) | KDM4EMAPTLMNAHTTHPGD | |
| SCHEMBL16480343 | 0.84 | MAPT (0.61) | KDM4EMAPTLMNAHTTHPGD | |
| SCHEMBL19072199 | 0.84 | MAPT (0.44) | KDM4EMAPTLMNAHTTHPGD | |
| SCHEMBL19072021 | 0.80 | KDM4E (0.63) | KDM4EMAPTLMNAHTTHPGD | |
| SCHEMBL14060851 | 0.78 | HPGD (0.41) | KDM4EMAPTLMNAHTTHPGD | |
| SCHEMBL16477951 | 0.78 | KDM4E (0.41) | KDM4EMAPTLMNAHTTHPGD | |
| SCHEMBL16480340 | 0.78 | KDM4E (0.41) | KDM4EMAPTLMNAHTTHPGD | |
| SCHEMBL19072009 | 0.76 | KDM4E (0.38) | KDM4EMAPTLMNAHTTHPGD | |
| SCHEMBL16477985 | 0.73 | KDM4E (0.45) | KDM4EMAPTLMNAHTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2714659-B1 | COMPOUNDS WITH OXIME ESTER AND/OR ACYL GROUPS | AMERICAN DYE SOURCE INC (CA) | 2017-07-05 | — | — | EP | disclosed |